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During embryonic development, the thyroid gland is being formed, beginning at the base of the tongue and moving towards the neck canal, known as the thyroglossal duct. Once the thyroid reaches its final position in the neck, the duct normally disappears. In some individuals, portions of the duct remain behind, leaving small pockets, known as cysts.
Most commonly an ultrasound is performed to confirm the presence of a nodule, and assess the status of the whole gland. Measurement of thyroid stimulating hormone and anti-thyroid antibodies will help decide if there is a functional thyroid disease such as Hashimoto's thyroiditis present, a known cause of a benign nodular goitre. [4]
As the developing thyroid begins to travel to its intended destination, it remains connected to the tongue via the thyroglossal duct. By the seventh week of fetal development, the thyroid reaches its final position in the neck after growing through the mesoderm and musculature of the tongue, mouth, and neck. During the eighth to tenth week, the ...
The pyramidal lobe is a remnant of the thyroglossal duct, which usually wastes away during the thyroid gland's descent. [5] Small accessory thyroid glands may in fact occur anywhere along the thyroglossal duct, from the foramen cecum of the tongue to the position of the thyroid in the adult. [4]
The thyroid gland is extremely painful, rigid, and swollen, which can be symmetrical or asymmetrical. [2] Approximately half of affected adolescents and two-thirds of adults have widespread thyroid gland involvement. [3] [5] Thyroid nodules are seen in one-fourth of adult patients. [6] The surrounding skin is occasionally warm and erythematous.
The thyroid cartilage is a hyaline cartilage structure that sits in front of the larynx and above the thyroid gland. The cartilage is composed of two halves, which meet in the middle at a peak called the laryngeal prominence, also called the Adam's apple. [1] In the midline above the prominence is the superior thyroid notch.
A goiter is a diffuse, often symmetric, swelling of the thyroid gland visible in the anterior neck that may develop. [13] The thyroid gland may become firm, large, and lobulated in Hashimoto's thyroiditis, but changes in the thyroid can also be non-palpable. [14] Enlargement of the thyroid is due to lymphocytic infiltration, and fibrosis. [15]
Thyroid disease is a medical condition that affects the structure and/or function of the thyroid gland. The thyroid gland is located at the front of the neck and produces thyroid hormones [1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ. These hormones normally act in the body to ...
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