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Flutamide has been researched and used extensively in the treatment of androgen-dependent skin and hair conditions in women including acne, seborrhea, hirsutism, and scalp hair loss, as well as in hyperandrogenism (e.g., in polycystic ovary syndrome or congenital adrenal hyperplasia), and is effective in improving the symptoms of these conditions.
Following a single oral dose of 2.5 mg tibolone, peak serum levels of tibolone were 1.6 ng/mL, of δ 4-tibolone were 0.8 ng/mL, of 3α-hydroxytibolone were 16.7 ng/mL, and of 3β-hydroxytibolone were 3.7 ng/mL after 1 to 2 hours. [1] The elimination half-life of tibolone is 45 hours. [8] It is excreted in urine 40% and feces 60%. [5] [8]
Dutasteride is also used in the treatment of male pattern hair loss and appears to have better effectiveness than finasteride for the condition. [27] [28] [29] While used off-label for male pattern hair loss in most of the world, dutasteride is specifically approved for this indication in South Korea and Japan. [30] [31]
Alfatradiol, also known as 17α-estradiol and sold under the brand names Avicis, Avixis, Ell-Cranell Alpha, and Pantostin, is a weak estrogen and 5α-reductase inhibitor medication which is used topically in the treatment of pattern hair loss (androgenic alopecia or pattern baldness) in men and women.
40–80 mg/2–4× day (with meals) Methyltestosterone b: Android, Metandren, Testred: Tablet: 10–50 mg/day Fluoxymesterone b: Halotestin, Ora-Testryl, Ultandren: Tablet: 5–20 mg/day Metandienone b: Dianabol: Tablet: 5–15 mg/day Mesterolone b: Proviron: Tablet: 25–150 mg/day Sublingual: Testosterone b: Testoral: Tablet: 5–10 mg 1–4 ...
Kopexil (INCI name diaminopyrimidine oxide, trade name Aminexil) is a chemical compound similar to minoxidil.Minoxidil was originally used to treat high blood pressure; a side effect was increased body hair.
Minoxidil, when applied topically, is used for the treatment of hair loss. [14] It is effective in helping promote hair growth in people with androgenic alopecia regardless of sex. [14] Minoxidil must be used indefinitely for continued support of existing hair follicles and the maintenance of any experienced hair regrowth. [6] [7]
Dutasteride is approved for the treatment of male androgenetic alopecia in South Korea and Japan at a dosage of 0.5 mg per day. [6] [17] Several studies have found it to induce hair regrowth in men more rapidly and to a greater extent than even the highest approved dosage of finasteride.
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