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Another important cell type is the pulmonary neuroendocrine cell. These are innervated cells that only make up around 0.5% of the respiratory epithelial cells. [7] The ciliated cells are columnar epithelial cells with specialized ciliary modifications. The ciliated cells make up between 50 and 80 per cent of the epithelium. [8]
Infection-induced iBALT structures contained CD4+ T cells, B220+ B cells (D), and CD21+ follicular dendritic cells (E). Bronchus-associated lymphoid tissue (BALT) is a tertiary lymphoid structure. It is a part of mucosa-associated lymphoid tissue (MALT), and it consists of lymphoid follicles in the lungs and bronchus. BALT is an effective ...
Micrograph showing hemosiderin-laden alveolar macrophages, as seen in a pulmonary hemorrhage. H&E stain.. An alveolar macrophage, pulmonary macrophage, (or dust cell) is a type of macrophage, a professional phagocyte, found in the airways and at the level of the alveoli in the lungs, but separated from their walls.
The pathological definition published by the World Health Organization is “a generalized proliferation of scattered single cells, small nodules (neuroendocrine bodies), or linear proliferations of pulmonary neuroendocrine (PNE) cells that may be confined to the bronchial and bronchiolar epithelium.” [1] The true prevalence of this disease ...
Diffuse alveolar damage (DAD): an acute lung condition with the presence of hyaline membranes. [2] These hyaline membranes are made up of dead cells, surfactant , and proteins. [ 1 ] The hyaline membranes deposit along the walls of the alveoli, where gas exchange typically occurs, thereby making gas exchange difficult.
Red arrows indicate secreted lamellar bodies, and green arrows indicate lamellar bodies in the cytoplasm. Scale bar = 200 nm. In cell biology, lamellar bodies (otherwise known as lamellar granules, membrane-coating granules (MCGs), keratinosomes or Odland bodies) are secretory organelles found in type II alveolar cells in the lungs, and in keratinocytes in the skin.
Lipid-laden alveolar macrophages in a case of vaping-associated pulmonary injury.Left: Papanicolaou stain; right: Oil Red O stain. [1]Lipid-laden alveolar macrophages, also known as pulmonary foam cells, [2] are cells found in bronchoalveolar lavage (BAL) specimens that consist of macrophages containing deposits of lipids (fats). [3]
Malignant club cells are also seen in bronchioalveolar carcinoma of the lung. Serum club cell proteins are used as a biomarker of lung permeability. Exposure to particulate air pollution may compromise the integrity of the lung epithelium and lead to rapid increase in epithelial barrier permeability, as reflected by increased serum club cell ...