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  2. Prostate-specific antigen - Wikipedia

    en.wikipedia.org/wiki/Prostate-specific_antigen

    Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene.PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland in men and the paraurethral glands in women.

  3. Prostate cancer screening - Wikipedia

    en.wikipedia.org/wiki/Prostate_cancer_screening

    Prostate cancer screening is the screening process used to detect undiagnosed prostate cancer in men without signs or symptoms. [1] [2] When abnormal prostate tissue or cancer is found early, it may be easier to treat and cure, but it is unclear if early detection reduces mortality rates.

  4. Prostate cancer staging - Wikipedia

    en.wikipedia.org/wiki/Prostate_cancer_staging

    From the AJCC 7th edition [5] and UICC 7th edition. [6]Stage I disease is cancer that is found incidentally in a small part of the sample when prostate tissue is removed for other reasons, such as benign prostatic hyperplasia, and the cells closely resemble normal cells and the gland feels normal to the examining finger.

  5. Gleason grading system - Wikipedia

    en.wikipedia.org/wiki/Gleason_grading_system

    It has been shown that this "modified Gleason score" has higher performance than the original one, and is currently assumed standard in urological pathology. In this form, it remains an important tool. [10] However, problematic aspects of the original Gleason grading system still characterize the 2005 revision.

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  7. Prostate cancer - Wikipedia

    en.wikipedia.org/wiki/Prostate_cancer

    Those with high levels of PSA in their blood are at increased risk for developing prostate cancer. Diagnosis requires a biopsy of the prostate. If cancer is present, the pathologist assigns a Gleason score; a higher score represents a more dangerous tumor. Medical imaging is performed to look for cancer that has spread outside the prostate.

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  9. Likelihood ratios in diagnostic testing - Wikipedia

    en.wikipedia.org/wiki/Likelihood_ratios_in...

    A medical example is the likelihood that a given test result would be expected in a patient with a certain disorder compared to the likelihood that same result would occur in a patient without the target disorder. Some sources distinguish between LR+ and LR−. [13] A worked example is shown below.

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