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The inbred strain of C57BL mice was created in 1921 by C. C. Little at the Bussey Institute for Research in Applied Biology. [1] The substrain "6" was the most popular of the surviving substrains.
Animal testing is widely used to aid in research of human disease when human experimentation would be unfeasible or unethical. [26] This strategy is made possible by the common descent of all living organisms, and the conservation of metabolic and developmental pathways and genetic material over the course of evolution. [27]
This facility was built for the purpose of live animal testing. Animals for experimentation were bred in the facility too, to provide sterile conditions and a maximum amount of control. It is located in close proximity to the Benjamin Franklin Medical Center and the Institute for Hygiene and Microbiology.
Charles River launched the Humane Care Imperative in 2002, designed to raise awareness and train employees on animal welfare's importance. The same year, they were named "Company of the Year" by The Boston Globe. The company introduced preconditioning services in 2005 to provide customers with study-ready animals.
BALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation.
The company was one of the largest participants in the international primate trade and has been criticized for its animal testing practices, most specifically animal testing on non-human primates as well as on beagles. The Stop Huntingdon Animal Cruelty campaign was formed with the goal of shutting down the company due to animal rights violations.
Killylea (/ k ɪ l iː ˈ l eɪ /; from Irish Coillidh Léith 'grey forest') is a small village and townland in Northern Ireland. It is within the Armagh City and District Council area. The village is set on a hill, with St Mark's Church of Ireland , built in 1832, at its summit.
The cartridges used in Cepheid's testing machines are single-use and must be bought from the manufacturer. The company has been accused of profiteering, particularly in developing countries, by pricing the cartridges at many times the cost of production, and engaging in price discrimination. [citation needed]