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Injector pens remove some of the complications of syringes by allowing the pen to be "pushed" against the skin at a 90-degree angle (removing the need to inject at a proper angle as is the case with syringes), as well as by replacing a long, thin plunger of a syringe with a simple button which is depressed and held to inject the dose.
U-100 syringe sizes and markings. 1cc (1 mL) Syringe Holds maximum: 100 units [10] Numbered in: 10 unit increments [10] Smallest line measures 2 units: [11] BD [10] ReliOn [12] Monoject [13] (all but 31 gauge needle) Smallest line measures 1 unit: Easy Touch [14] Precision Sure Dose [13] 1/2cc (0.5 mL) Syringe Holds maximum: 50 units [15 ...
Insulin can not be taken orally because insulin is a hormone and is destroyed by the digestive track. Insulin can be injected by several methods, including a hypodermic needle, jet injector, or insulin pump. There is also inhaled insulin that can be used in adults with diabetes. [33]
The advent of the first low dead space syringe occurred with the creation of 1-ml syringes designed specifically for the administration of insulin. Then amongst the scare of HIV and rising concern of other communicable diseases to healthcare workers the creation of safety syringes occurred in 1988.
The trend of needle specification for use began in the 1920s, particularly for the administration of insulin to diabetics. [ 14 ] The onset of World War II spurred the early development of partially disposable syringes for the administration of morphine and penicillin on the battlefield.
While attempts have been made since the 1920s to administer insulin orally, the large size of the molecule has made it difficult to create a formulation with absorption and predictability that comes close to subcutaneous injections of insulin. [5] People with type 1 diabetes almost all require insulin as part of their treatment regimens, and a ...
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