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NSAIDs cause decreased ability to form blood clots, which can increase the risk of bleeding when combined with other drugs that also decrease blood clotting, such as warfarin. [113] NSAIDs may aggravate hypertension (high blood pressure) and thereby antagonize the effect of antihypertensives, [113] such as ACE inhibitors. [114]
Long-term use of NSAIDs can cause gastric erosions, which can become stomach ulcers and in extreme cases can cause severe haemorrhage, resulting in death. The risk of death as a result of GI bleeding caused by the use of NSAIDs is 1 in 12,000 for adults aged 16–45. [5] The risk increases almost twentyfold for those over 75. [5]
In addition to NSAID-related bleeding, another common cause of bleeding is that related to the medication, warfarin ("Coumadin" and others). This medication needs to be closely monitored as the bleeding risk can be markedly increased by interactions with other medications. Warfarin acts by inhibiting the production of Vitamin K in the gut ...
[178] [179] People with hemophilia or other bleeding tendencies should not take aspirin or other salicylates. [178] [182] Aspirin is known to cause hemolytic anemia in people who have the genetic disease glucose-6-phosphate dehydrogenase deficiency, particularly in large doses and depending on the severity of the disease. [183]
NSAIDs, naproxen and aspirin. Blood thinners and anticoagulants, like warfarin, due to risk of abnormal bleeding. Triptans and medications used to treat migraines like sumatriptan. Water pills ...
Once infectious causes ruled out, noninfectious causes should be investigated. These include a history of chemical irritation from recent surgery or chemicals injected into the subarachnoid space such as spinal anesthesia , other inflammatory or vascular conditions such as sarcoidosis or vasculitis , as well as Neoplastic conditions such as ...
She emphasizes that studies have shown that turmeric supplementation can be as effective as some nonsteroidal anti-inflammatory drugs (NSAIDs) in relieving osteoarthritis symptoms without the ...
Medical condition Subarachnoid hemorrhage Other names Subarachnoid haemorrhage CT scan of the brain showing subarachnoid hemorrhage as a white area in the center (marked by the arrow) and stretching into the sulci to either side Pronunciation / ˌ s ʌ b ə ˈ r æ k n ɔɪ d ˈ h ɛ m ər ɪ dʒ / Specialty Neurosurgery, Neurology Symptoms Severe headache of rapid onset, vomiting, decreased ...