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The weakening of the skin's protective layers forms an environment susceptible to microbial infiltration, which could lead to severe complications. Intervening within an earlier time frame and targeted management strategies are essential to minimize further adverse effects. [10] Another autoimmune skin disease which can occur in dogs is vitiligo.
The condition of a dog's skin and coat is also an important indicator of its general health. Skin disorders of dogs vary from acute, self-limiting problems to chronic or long-lasting problems requiring life-time treatment. Skin disorders may be primary or secondary (due to scratching, itch) in nature, making diagnosis complicated.
Bruch's membrane thickens with age, slowing the transport of metabolites. This may lead to the formation of drusen in age-related macular degeneration. [4] There is also a buildup of deposits (Basal Linear Deposits or BLinD and Basal Lamellar Deposits BLamD) on and within the membrane, primarily consisting of phospholipids.
The retinal degeneration appears to be related to apoptosis of these cells. [11] SARDS must be distinguished from other causes of sudden blindness that have no visible pathology, including retrobulbar optic neuritis , a tumor at the optic chiasm , or other central nervous system diseases.
Recently, central serous chorioretinopathy has been understood to be part of the pachychoroid spectrum. [5] [6] In pachychoroid spectrum disorders, of which CSR represents stage II, the choroid, the highly vascularized layer below the retina, is thickened and congested with increased blood vessel diameter, especially in the deep choroid (the so-called Haller's layer).
Dermoid sinus a genetic, autosomal skin condition in dogs. It can appear as single or multiple lumps on the dorsal midline. [34] Lick granuloma from excessive licking. Lick granuloma also known as acral lick dermatitis, is a skin disorder in dogs resulting from an urge to lick the lower portion of the leg. The lesion from the incessant licking ...
Progressive retinal atrophy (PRA) is a group of genetic diseases seen in certain breeds of dogs and, more rarely, cats. Similar to retinitis pigmentosa in humans, [ 1 ] it is characterized by the bilateral degeneration of the retina , causing progressive vision loss culminating in blindness.
The dark blue, teal, and gold tapetum lucidum from the eye of a cow Retina of a mongrel dog with strong tapetal reflex. The tapetum lucidum (Latin for 'bright tapestry, coverlet'; / t ə ˈ p iː t əm ˈ l uː s ɪ d əm / tə-PEE-təm LOO-sih-dəm; pl.: tapeta lucida) [1] is a layer of tissue in the eye of many vertebrates and some other animals.