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Structural formula of staurosporine, the first indolocarbazole to be isolated. Indolocarbazoles (ICZs) are a class of compounds that are under current study due to their potential as anti-cancer as well as antimicrobial drugs and the prospective number of derivatives and uses found from the basic backbone alone.
The conjugate transpose of a matrix with real entries reduces to the transpose of , as the conjugate of a real number is the number itself. The conjugate transpose can be motivated by noting that complex numbers can be usefully represented by 2 × 2 {\displaystyle 2\times 2} real matrices, obeying matrix addition and multiplication: a + i b ≡ ...
Staurosporine is an indolocarbazole. It belongs to the most frequently isolated group of indolocarbazoles: Indolo(2,3-a)carbazoles. Of these, Staurosporine falls within the most common subgroup, called Indolo(2,3-a)pyrrole(3,4-c)carbazoles. These fall into two classes - halogenated (chlorinated) and non-halogenated.
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In mathematics, the complex conjugate of a complex number is the number with an equal real part and an imaginary part equal in magnitude but opposite in sign. That is, if a {\displaystyle a} and b {\displaystyle b} are real numbers, then the complex conjugate of a + b i {\displaystyle a+bi} is a − b i . {\displaystyle a-bi.}
To obtain many of many of these bonds the use of peptides or amino acids. There is a strong desire to synthesize polymeric conjugates with bioactive components and other drugs. The tendency of polymer drug conjugate to react with the proper type cell(s) needs to still be worked on, despite many current advances. [5]
The irreducible complex characters of a finite group form a character table which encodes much useful information about the group G in a concise form. Each row is labelled by an irreducible character and the entries in the row are the values of that character on any representative of the respective conjugacy class of G (because characters are class functions).
Topoisomerase inhibitor classes have been derived from a wide variety of disparate sources, with some being natural products first extracted from plants (camptothecin, [10] etoposide [13]) or bacterial samples (doxorubicin, [14] indolocarbazole [15]), while others possess purely synthetic, and often accidental, origins (quinolone, [11 ...