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1–5.4% of global population [4] 1918–1920 Worldwide 2 Plague of Justinian: Bubonic plague 15–100 million 25–60% of European population [5] 541–549 North Africa, Europe, and Western Asia 3 HIV/AIDS pandemic: HIV/AIDS: 44 million (as of 2025) – 1981–present [6] Worldwide 4 Black Death: Bubonic plague: 25–50 million
In 1918–1919, 99% of pandemic influenza deaths in the U.S. occurred in people under 65, and nearly half of deaths were in young adults 20 to 40 years old. In 1920, the mortality rate among people under 65 had decreased sixfold to half the mortality rate of people over 65, but 92% of deaths still occurred in people under 65. [ 300 ]
The Hong Kong flu was a category 2 flu pandemic caused by a strain of H3N2 descended from H2N2 by antigenic shift, in which genes from multiple subtypes reassorted to form a new virus. This pandemic killed an estimated 1–4 million people worldwide. [83] [92] [93] Those over 65 had the greatest death rates. [94]
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
The 1918–1920 flu pandemic is commonly referred to as the Spanish flu, and caused millions of deaths worldwide. To maintain morale, wartime censors minimized early reports of illness and mortality in Germany , the United Kingdom , France , and the United States .
For the 1918 flu, people infected numbers (500 million), mortality rate (2~3%) contradict the deaths worldwide "20–100 million" statements. Review needed. Lead: Johnson NPAS, Mueller (2002). "Updating the Accounts: Global Mortality of the 1918–1920 Spanish Influenza Pandemic". Kilbourne ED (January 2006). "Influenza pandemics of the 20th ...
This is a timeline of influenza, briefly describing major events such as outbreaks, epidemics, pandemics, discoveries and developments of vaccines.In addition to specific year/period-related events, there is the seasonal flu that kills between 250,000 and 500,000 people every year and has claimed between 340 million and 1 billion human lives throughout history.
Flu statistics are often compared to coronavirus statistics. COVID-19 pandemic cases. More statistics for comparison purposes. COVID-19 pandemic deaths. More statistics for comparison purposes. Influenza vaccine; Bird flu; Human flu; Swine flu; Horse flu; Dog flu; Freshers' flu; 2012–2013 flu season; 2017–2018 United States flu season; 2019 ...