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Simple renal cyst. A renal cyst is a fluid collection in or on the kidney. There are several types based on the Bosniak classification. The majority are benign, simple cysts that can be monitored and not intervened upon. However, some are cancerous or are suspicious for cancer and are commonly removed in a surgical procedure called nephrectomy.
This is an accepted version of this page This is the latest accepted revision, reviewed on 21 February 2025. Medical condition Kidney cancer Other names Renal cancer Micrograph showing the most common type of kidney cancer (clear cell renal cell carcinoma). H&E stain. Specialty Oncology nephrology Urology Symptoms Blood in the urine, lump in the abdomen, back pain Usual onset After the age of ...
Renal cell carcinoma (RCC) is a kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney that transport primary urine. RCC is the most common type of kidney cancer in adults, responsible for approximately 90–95% of cases. [ 1 ]
Multilocular cystic renal cell carcinoma (MCRCC) is rare subtype of renal cell carcinoma. Histologically, the tumor has a fibrous capsule and contains multiple cysts with clear cells. [1] 1-5% of renal cell carcinomas are MCRCC. [1]
Like other cancers, kidney cancer is measured in stages. •Stage 1, the tumour has not spread and is localized. This accounts for 65% of cases of kidney cancer and 92.5% of people with stage 1 kidney cancer survive 5 years. •Stage 2 and 3, the tumour has grown larger and has spread and started to affect regional tissues and lymph nodes.
The number and size of cysts and kidney volume are predictors for the progression of CKD and end-stage renal disease. PKD does not increase the risk for the development of renal cancer, but if such develops, it is more likely to be bilateral. The most probable cause of death is heart disease, ruptured cerebral aneurysm, or disseminated infection.
Papillary renal cell carcinoma (PRCC) is a malignant, heterogeneous tumor originating from renal tubular epithelial cells of the kidney, which comprises approximately 10-15% of all kidney neoplasms. [1] Based on its morphological features, PRCC can be classified into two main subtypes, which are type 1 and type 2 (eosinophilic). [2]
Cysts lined by a simple epithelium with a hobnail morphology, i.e. the nuclei of the cyst lining epithelium bulges into the lumen of the cysts, Ovarian-like stroma that has a: Spindle cell morphology, and has a; Basophilic cytoplasm. Cystic nephromas have an immunostaining pattern like ovarian stroma; they are positive for: Estrogen receptor (ER),