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The comprehensive metabolic panel, or chemical screen (CMP; CPT code 80053), is a panel of 14 blood tests that serves as an initial broad medical screening tool. The CMP provides a rough check of kidney function, liver function, diabetic and parathyroid status, and electrolyte and fluid balance, but this type of screening has its limitations.
This is commonly ordered when liver disease is suspected as part of a comprehensive metabolic panel (CMP) in conjunction with the electrolyte panel known as the basic metabolic panel (BMP). In kidney disease, a CMP may be ordered as a follow-up test when proteinuria is detected by urine dipstick analysis , which may lead to a diagnosis of ...
a group of blood tests (albumin, alkaline phosphatase, ... CMP: complete metabolic profile (a blood panel)
Albumin is a protein made specifically by the liver, and can be measured cheaply and easily. It is the main constituent of total protein (the remaining constituents are primarily globulins). Albumin levels are decreased in chronic liver disease, such as cirrhosis. It is also decreased in nephrotic syndrome, where it is lost through the urine.
It may be reported with the results of an electrolyte panel, which is often performed as part of a comprehensive metabolic panel. [3] The anion gap is the quantity difference between cations (positively charged ions) and anions (negatively charged ions) in serum, plasma, or urine.
Next a blood screen, comprehensive metabolic panel (CMP) will look for hypoalbuminemia: albumin levels of ≤2.5 g/dL (normal=3.5-5 g/dL). Then a Creatinine Clearance C Cr test will evaluate kidney function particularly the glomerular filtration capacity. [36]
A basic metabolic panel including calcium is sometimes colloquially referred to as a "CHEM-8". Calcium, as an alkaline earth metal , is also an electrolyte, but abnormalities are more commonly associated with malnutrition, osteoporosis , or malignancy , especially of the thyroid .
Concentrations below the reference range usually reflect low albumin concentration, for instance in liver disease or acute infection. Rarely, low total protein may be a sign of immunodeficiency . Concentrations above the reference range are found in paraproteinaemia , Hodgkin's lymphoma , leukaemia or any condition causing an increase in ...