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The study found a 39% lower HIV infection rate in women using 1% tenofovir gel compared with women using a placebo gel. In addition, tenofovir gel was shown to be safe as tested. [ 21 ] The results of the CAPRISA 004 trial provide statistically significant evidence that ARVs, topically applied to the vaginal mucosa, can offer protection against ...
PVP-I is approved for treatment of bacterial vaginosis as a vaginal gel. [18] [19] [20] Brand names include Astodrimer Sodium or Astrodimer 1% Vaginal Gel, Betadine BV, Betafem BV, Viraleze, and VivaGel, among others. [18] [19] [20] Vaginal suppositories are also available and used. [21]
The ideal vaginal microbicide would have the following characteristics: provide protection against infection not require application at the time of intercourse not harm the natural tissue [3] As of 2009, not harming natural tissue was the most troublesome aspect of development.
The trial involved 222 men, ages 18 to 50, who applied 5 milliliters of the gel (about a teaspoon) to each of their shoulder blades once per day. The second part of the two-part trial is still ...
It is used as an administration method for issues related to women's health, such as contraception. [5] Medicines primarily delivered by intravaginal administration include vaginally administered estrogens and progestogens (a group of hormones including progesterone ), and antibacterials and antifungals to treat bacterial vaginosis and yeast ...
To help you find the best products for your lifestyle and budget, I spoke with six doctors and dermatologists about the science behind aging, what ingredients and textures to look for in skin care ...
For example, a failure rate of 20% means that 20 of 100 women become pregnant during the first year of use. Note that the rate may go above 100% if all women, on average, become pregnant within less than a year. In the degenerated case of all women becoming pregnant instantly, the rate would be infinite.
Nonoxynol-9 is a common ingredient of most vaginal and anal lubricants due to its spermicidal properties. A 2004 study found that over a six-month period, the typical-use failure rates for five nonoxynol-9 vaginal contraceptives (film, suppository, and gels at three different concentrations) ranged from 10% to 20%.
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