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The threshold dose is only a measure of acute toxicity since the drug or toxic substance investigated is administered at once. The consequence of long-term administration remains unknown. [27] As the threshold dose is the measured minimal response, its accuracy heavily depends on the machinery used. It is possible that further refinement is ...
Threshold limit value − ceiling limit (TLV-C): An absolute exposure limit that should not be exceeded at any time. There are TLVs for physical agents as well as chemical substances. TLVs for physical agents include those for noise exposure, vibration, ionizing and non-ionizing radiation exposure and heat and cold stress.
Odor threshold value (OTV) (also aroma threshold value (ATV), Flavor threshold) is defined as the most minimal concentration of a substance that can be detected by a human nose. Some substances can be detected when their concentration is only few milligrams per 1000 tonnes, which is less than a drop in an Olympic swimming pool. Odor threshold ...
Many gases have toxic properties, which are often assessed using the LC 50 (median lethal concentration) measure. In the United States, many of these gases have been assigned an NFPA 704 health rating of 4 (may be fatal) or 3 (may cause serious or permanent injury), and/or exposure limits (TLV, TWA/PEL, STEL, or REL) determined by the ACGIH professional association.
In analytical chemistry, the detection limit, lower limit of detection, also termed LOD for limit of detection or analytical sensitivity (not to be confused with statistical sensitivity), is the lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value) with a stated confidence level (generally 99%).
Denatonium, usually available as denatonium benzoate (under trade names such as Denatrol, BITTERANT-b, BITTER+PLUS, Bitrex, Bitrix, and Aversion) and as denatonium saccharinate (BITTERANT-s), is the most bitter chemical compound known, with bitterness thresholds of 0.05 ppm for the benzoate and 0.01 ppm for the saccharinate. [1]
The World Health Organization (WHO) names four toxicity classes: . Class I – a: extremely hazardous; Class I – b: highly hazardous; Class II: moderately hazardous; Class III: slightly hazardous
An occupational exposure limit is an upper limit on the acceptable concentration of a hazardous substance in workplace air for a particular material or class of materials. It is typically set by competent national authorities and enforced by legislation to protect occupational safety and health.