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Extracts of bitter orange and its peel have been marketed as dietary supplements purported to act as a weight-loss aid and appetite suppressant. [32] [33] Bitter orange contains the tyramine metabolites N-methyltyramine, octopamine, and synephrine, [34] substances similar to epinephrine, which act on the α 1 adrenergic receptor to constrict ...
Bitter orange extract is found in citrus fruits such as Seville oranges and contains synephrine, a stimulant with effects similar to ephedrine, according to a 2017 study published in Phytotherapy ...
Extracts of unripe fruit from Asian cultivars of Citrus aurantium (commonly known as "bitter" orange), collected in China, were reported to contain synephrine levels of about 0.1–0.3%, or ~1–3 mg/g; [10] Analysis of dried fruit of C. aurantium grown in Italy showed a concentration of synephrine of ~1 mg/g, with peel containing over three times more than the pulp.
What is an appetite suppressant? On a basic level, an appetite suppressant is anything that impacts your desire to eat, says dietitian Scott Keatley, RD, co-owner of Keatley Medical Nutrition Therapy.
Sibutramine, formerly sold under the brand name Meridia among others, is an appetite suppressant which has been discontinued in many countries. It works as a serotonin–norepinephrine reuptake inhibitor (SNRI) similar to certain antidepressants.
The good news is that there are plenty of healthy and effective ways to suppress your appetite for weight loss without resorting to extreme measures. From simple lifestyle changes to smart food ...
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