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Typically, the itching is localized to the palms of the hands and soles of the feet, but can be anywhere on the body. Hallmarks of ICP include the following symptoms: [5] Most common: Itching, in particular but not limited to that of the palms of the hands and soles of the feet, without presence of a rash; Itching that is more noticeable in the ...
Cholestatic pruritus is the sensation of itch due to nearly any liver disease, but the most commonly associated entities are primary biliary cholangitis, primary sclerosing cholangitis, obstructive choledocholithiasis, carcinoma of the bile duct, cholestasis (also see drug-induced pruritus), and chronic hepatitis C viral infection and other forms of viral hepatitis.
In medicine, the presence of elevated transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver dysfunction. [ 1 ] [ 2 ] Other terms include transaminasemia , [ 3 ] and elevated liver enzymes (though they are not the only enzymes in the liver).
Dry skin and dry eyes are also common. Itching occurs in 20–70% of cases, [4] and can develop at any stage of the disease. Textbooks tend to describe itching in the feet and hands, but patients may also experience itching of the scalp, face, back, or other areas. The itching is typically mild-to-moderate in intensity.
Once fully developed, the effected skin will present with a leathery, "bark-like" texture and remain itchy and inflamed. [3] Common areas of occurrence are noted in points of the body that are easily accessible or prone to itchiness, notably the nape of the neck, wrists, hands, forearms, waist, scrotum, vulva, thighs, lower legs and feet. [4]
The symptoms of seborrhoeic dermatitis, on the other hand, tend to appear gradually, from dry or greasy scaling of the scalp to scaling of facial areas, sometimes with itching, but without hair loss. [22] In newborns, the condition causes a thick and yellowish scalp rash, often accompanied by a diaper rash.
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Dyshidrosis is a type of dermatitis, characterized by itchy vesicles of 1–2 mm in size, on the palms of the hands, sides of fingers, or bottoms of the feet. [8] Outbreaks usually conclude within three to four weeks, but often recur. [4] [8] Repeated attacks may result in fissures and skin thickening. [7] The cause of the condition is not ...