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The presence of eosinophils in the esophagus may be due to an allergen and is often correlated with GERD. The direction of cause and effect between inflammation and acid reflux is poorly established, with recent studies (in 2016) hinting that reflux does not cause inflammation. [6]
GERD can cause inflammation of the lower esophagus caused by chronic acid reflux, making it hard to swallow. Related: The 7-Day GERD Diet Plan Registered Dietitians Swear By
Esophageal strictures – the persistent narrowing of the esophagus caused by reflux-induced inflammation; Barrett's esophagus – intestinal metaplasia (changes of the epithelial cells from squamous to intestinal columnar epithelium) of the distal esophagus [20] Esophageal adenocarcinoma – a form of cancer [17]
“Persistent acid reflux over time can cause inflammation within the esophagus,” says Dr. Mona Rezapour, MD, a HealthCentral gastroenterologist and medical reviewer.
The H 2 receptor antagonists are a class of drugs used to block the action of histamine on parietal cells in the stomach, decreasing the production of acid by these cells. H 2 antagonists are used in the treatment of dyspepsia, although they have been surpassed in popularity by the more effective [1] proton pump inhibitors.
Heartburn, also known as pyrosis, cardialgia or acid indigestion, [2] is a burning sensation in the central chest or upper central abdomen. [3] [4] [5] Heartburn is usually due to regurgitation of gastric acid (gastric reflux) into the esophagus.
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