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Simple liver cysts are seen most commonly in women and kids. [2] In terms of pathophysiology, they are formed in response to developmental events and in response to trauma and inflammation. [ 2 ] In addition, liver cysts can be seen with polycystic kidney disease and echinococcosis infection ( hydatid disease ).
Polycystic liver disease (PLD) usually describes the presence of multiple cysts scattered throughout normal liver tissue. [1] PLD is commonly seen in association with autosomal-dominant polycystic kidney disease , with a prevalence of 1 in 400 to 1000, and accounts for 8–10% of all cases of end-stage renal disease . [ 2 ]
The cause appears to be genetic; the simple form is an autosomal dominant trait, while the complex form is an autosomal recessive trait. [2] Females are more prone to Caroli disease than males. [ 8 ] Family history may include kidney and liver disease due to the link between Caroli disease and ARPKD . [ 6 ]
von Meyenburg Complex in ultrasound. Numerous little cysts with ringdown artefacts. Laboratory findings include high transaminase levels, raised gamma-glutamyl transferase or alkaline phosphatase levels, increased C-reactive protein , hypoalbuminemia , and hematologic abnormalities like thrombocytopenia , leukopenia , leukocytosis , and anemia .
Liver cancer can be primary in which the cancer starts in the liver, or it can be liver metastasis, or secondary, in which the cancer spreads from elsewhere in the body to the liver. Liver metastasis is the more common of the two liver cancers. [3] Instances of liver cancer are increasing globally. [8] [9]
Benign liver tumors generally develop on normal or fatty liver, are single or multiple (generally paucilocular), have distinct delineation, with increased echogenity (hemangiomas, benign focal nodular hyperplasia) or absent, with posterior acoustic enhancement effect (cysts), have distinct delineation (hydatid cyst), lack of vascularization or show a characteristic circulatory pattern ...
Cystic kidney disease includes various conditions related to the formation of cysts in one or both kidneys. The most common subset is polycystic kidney disease (PKD), which is a genetic anomaly with two subsets, autosomal recessive polycystic kidney disease (ARPKD) and autosomal dominant polycystic kidney disease (ADPKD).
Liver transplantation, replacing the diseased liver with a cadaveric or a living donor liver, plays an increasing role in treatment of HCC. Although outcomes following liver transplant were initially poor (20%–36% survival rate), [ 20 ] outcomes have significantly improved with improvement in surgical techniques and adoption of the Milan ...