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Lubiprostone received approval from the Food and Drug Administration in 2008, to treat irritable bowel syndrome with constipation (IBS-C), [7] and in 2013, for the treatment of opioid-induced constipation in adults with chronic noncancer pain. [4] It is available as a generic medication. [8]
Rectal suppositories are intended for localized or systemic action to relieve pain, constipation, irritation, inflammation, nausea and vomiting, fever, migraines, allergies, and sedation. [ 7 ] [ 8 ] If they cause inflammation, chronic use of suppositories may cause rectal stricture , [ 9 ] but overall this is a safe method of drug delivery.
Macrogol 4000, pharmaceutical quality. Macrogol 3350, often in combination with electrolytes, is used for short-term relief of constipation as well as for long-term use in constipation of various causes, including in multiple sclerosis and Parkinson's disease patients (an often-overlooked non-motor symptom) as well as constipation caused by pharmaceutical drugs such as opioids and ...
They are used to treat and prevent constipation. Laxatives vary as to how they work and the side effects they may have. Certain stimulant , lubricant , and saline laxatives are used to evacuate the colon for rectal and bowel examinations, and may be supplemented by enemas under certain circumstances.
In addition to pharmacological effects, rectal administration has some properties which can be advantageous for the use in medicine. Rectal administration can allow patients to remain in the home setting when the oral route is compromised.
Estimation of the dietary nutrient profile of free-roaming feral cats: possible implications for nutrition of domestic cats. Br J Nutr. 2011 Oct;106 Suppl 1:S35-48. doi: 10.1017/S0007114511002285 ...
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