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The lacrimal gland is a compound tubuloacinar gland, it is made up of many lobules separated by connective tissue, each lobule contains many acini.The acini composed of large serous cells which, produce a watery serous secretion, serous cells are filled with lightly stained secretory granules and surrounded by well-developed myoepithelial cells and a sparse, vascular stroma.
The lacrimal apparatus is the physiological system containing the orbital structures for tear production and drainage. [1]It consists of: The lacrimal gland, which secretes the tears, and its excretory ducts, which convey the fluid to the surface of the eye; it is a j-shaped serous gland located in lacrimal fossa.
The lacrimal apparatus is the physiological system containing the orbital structures for tear production and drainage. [3] It consists of: The lacrimal gland, which secretes the tears, and its excretory ducts, which convey the fluid to the surface of the human eye; it is a serous gland located in lacrimal fossa. It is a j-shaped gland;
Involutional stenosis is probably the most common cause of nasolacrimal duct obstruction in older people. It affects women twice as frequently as men. Although the inciting event in this process is unknown, clinicopathologic study suggests that compression of the lumen of the nasolacrimal duct is caused by inflammatory infiltrates and edema.
Previously it was thought that the main lacrimal gland is responsible for reflex tear secretion and the accessory lacrimal glands of Wolfring and Krause are responsible for the basal secretion. But recent evidence suggests that all tearing may be reflex. [5] The accessory glands account for approximately 10% of the total lacrimal secretory mass ...
Historically, bilateral parotid and lacrimal gland enlargement was characterized by the term Mikulicz's disease if the enlargement appeared apart from other diseases. If it was secondary to another disease, such as tuberculosis, sarcoidosis, lymphoma, and Sjögren's syndrome, the term used was Mikulicz's syndrome.
90070 n/a Ensembl ENSG00000135413 n/a UniProt Q9GZZ8 n/a RefSeq (mRNA) NM_033277 n/a RefSeq (protein) NP_150593 n/a Location (UCSC) Chr 12: 54.63 – 54.63 Mb n/a PubMed search n/a Wikidata View/Edit Human Lacritin is a 12.3 kDa glycoprotein encoded in humans by the LACRT gene. Lacritin's discovery emerged from a screen for factors that stimulate tear protein secretion. Lacritin is a secreted ...
Keratoconjunctivitis sicca can be caused by inadequate tear production from lacrimal hyposecretion. [13] [14] The aqueous tear layer is affected, resulting in aqueous tear deficiency (ATD). [14] The lacrimal gland does not produce sufficient tears to keep the entire conjunctiva and cornea covered by a complete layer. [13]