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Bioinformatics is the name given to these mathematical and computing approaches used to glean understanding of biological processes. Common activities in bioinformatics include mapping and analyzing DNA and protein sequences, aligning DNA and protein sequences to compare them, and creating and viewing 3-D models of protein structures.
Machine learning in bioinformatics is the application of machine learning algorithms to bioinformatics, [1] including genomics, proteomics, microarrays, systems biology, evolution, and text mining. [ 2 ] [ 3 ]
BioPerl is an active open source software project supported by the Open Bioinformatics Foundation.The first set of Perl codes of BioPerl was created by Tim Hubbard and Jong Bhak [citation needed] at MRC Centre Cambridge, where the first genome sequencing was carried out by Fred Sanger.
Bioinformatics and computational biology are interdisciplinary fields of research, development and application of algorithms, computational and statistical methods for management and analysis of biological data, and for solving basic biological problems.
Biological data has also been difficult to define, as bioinformatics is a wide-encompassing field. Further, the question of what constitutes as being a living organism has been contentious, as "alive" represents a nebulous term that encompasses molecular evolution, biological modeling, biophysics, and systems biology.
BioJava is an open-source software project dedicated to provide Java tools to process biological data. [1] [2] [3] BioJava is a set of library functions written in the programming language Java for manipulating sequences, protein structures, file parsers, Common Object Request Broker Architecture (CORBA) interoperability, Distributed Annotation System (DAS), access to AceDB, dynamic ...
Relational database concepts of computer science and Information retrieval concepts of digital libraries are important for understanding biological databases. Biological database design, development, and long-term management is a core area of the discipline of bioinformatics. [3]
Open Bioinformatics Foundation: BioPerl: Perl language toolkit Cross-platform: Artistic, GPL: Open Bioinformatics Foundation: BioPHP: PHP language toolkit with classes for DNA and protein sequence analysis, alignment, database parsing, and other bioinformatics tools Cross-platform: GPL v2 Open Bioinformatics Foundation: Biopython: Python ...