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  2. Hepatotoxicity - Wikipedia

    en.wikipedia.org/wiki/Hepatotoxicity

    Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents.

  3. Hy's law - Wikipedia

    en.wikipedia.org/wiki/Hy's_law

    Hy's law is a rule of thumb that a patient is at high risk of a fatal drug-induced liver injury if given a medication that causes hepatocellular injury (not Hepatobiliary injury) with jaundice. [1] The law is based on observations by Hy Zimmerman, a major scholar of drug-induced liver injury.

  4. Glucuronidation - Wikipedia

    en.wikipedia.org/wiki/Glucuronidation

    UDP-glucuronic acid (glucuronic acid linked via a glycosidic bond to uridine diphosphate) is an intermediate in the process and is formed in the liver. One example is the N-glucuronidation of an aromatic amine, 4-aminobiphenyl, by UGT1A4 or UGT1A9 from human, rat, or mouse liver. [2]

  5. Liver disease - Wikipedia

    en.wikipedia.org/wiki/Liver_disease

    Analogous terms such as "drug-induced" or "toxic" liver disease are also used to refer to disorders caused by various drugs. [7] Fatty liver disease (hepatic steatosis) is a reversible condition where large vacuoles of triglyceride fat accumulate in liver cells. [8]

  6. Hepatic veno-occlusive disease - Wikipedia

    en.wikipedia.org/wiki/Hepatic_veno-occlusive_disease

    Hepatic veno-occlusive disease (VOD) or veno-occlusive disease with immunodeficiency is a potentially life-threatening condition in which some of the small veins in the liver are obstructed. It is a complication of high-dose chemotherapy given before a bone marrow transplant or excessive exposure to hepatotoxic pyrrolizidine alkaloids .

  7. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/projects/dying-to-be...

    Karyn Hascal, The Healing Place’s president and CEO, said she would never allow Suboxone in her treatment program because her 12-step curriculum is “a drug-free model. There’s kind of a conflict between drug-free and Suboxone.” For policymakers, denying addicts the best scientifically proven treatment carries no political cost.

  8. Paracetamol poisoning - Wikipedia

    en.wikipedia.org/wiki/Paracetamol_poisoning

    Paracetamol overdose results in more calls to poison control centers in the US than overdose of any other pharmacological substance, accounting for more than 100,000 calls, as well as 56,000 emergency room visits, 2,600 hospitalizations, and 458 deaths due to acute liver failure per year. [95]

  9. 5 Cheeses You Have to Try from Aldi, According to Customers - AOL

    www.aol.com/5-cheeses-try-aldi-according...

    $1.89 per 8-ounce block. Sharp Cheddar is a well-deserved favorite among Aldi shoppers, and it’s easy to see why. Its bold, tangy flavor makes it the perfect addition to nearly any dish.