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The long-term impact of alcohol on the brain has become a growing area of research focus. While researchers have found that moderate alcohol consumption in older adults is associated with better cognition and well-being than abstinence, [ 1 ] excessive alcohol consumption is associated with widespread and significant brain lesions .
Alcohol-related brain damage [1] [2] alters both the structure and function of the brain as a result of the direct neurotoxic effects of alcohol intoxication or acute alcohol withdrawal. Increased alcohol intake is associated with damage to brain regions including the frontal lobe , [ 3 ] limbic system , and cerebellum , [ 4 ] with widespread ...
Alcohol acts as a general central nervous system depressant, but it also affects some specific areas of the brain to a greater extent than others. Memory impairment caused by alcohol has been linked to the disruption of hippocampal function—particularly affecting gamma-Aminobutyric acid (GABA) and N-methyl-D-aspartate (NMDA) neurotransmission which negatively impacts long-term potentiation ...
Addiction to alcohol, as with any addictive substance tested so far, has been correlated with an enduring reduction in the expression of GLT1 in the nucleus accumbens and is implicated in the drug-seeking behavior expressed nearly universally across all documented addiction syndromes. This long-term dysregulation of glutamate transmission is ...
We’ve all seen the headlines: “6 Reasons Why a Little Glass of Wine Each Day May Do You Good,” or “Study Finds Drinking Wine with Meals Was Associated with Lower Risk of Type 2 Diabetes.”
“(Alcohol) is going in and obliterating the brain cells,” Nicola says. This kind of deterioration is responsible for disease like Alzheimer's, which we can lower the risk for when we cut down ...
Alcohol (also known as ethanol) has a number of effects on health. Short-term effects of alcohol consumption include intoxication and dehydration. Long-term effects of alcohol include changes in the metabolism of the liver and brain, with increased risk of several types of cancer and alcohol use disorder. [1]
It can also lead to long-term health effects, such as liver disease if done on a regular basis. A September 2024 study reported that excessive alcohol use was linked to a higher risk of six types ...