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It is the major cause of liver disease in Western countries, and is the leading cause of death from excessive drinking. [2] [3] Although steatosis (fatty liver disease) will develop in any individual who consumes a large quantity of alcoholic beverages over a long period of time, this process is transient and reversible. [1]
Non-alcoholic fatty liver disease prevalence in 2019. MASLD incidence is rapidly rising, along with obesity and diabetes, and has become the most common cause of liver disease in developed countries, for adults, teenagers, and children. [24] [25] The percentage of people with MASLD ranges from 9 to 36.9% in different parts of the world.
The cause of cirrhosis can vary; alcohol and non-alcoholic fatty liver disease are main causes in western and industrialized countries, whereas viral hepatitis is the predominant cause in low and middle-income countries. [154] Cirrhosis is more common in men than in women. [156]
High consumption of alcohol can lead to several forms of liver disease including alcoholic hepatitis, alcoholic fatty liver disease, cirrhosis, and liver cancer. [42] In the earlier stages of alcoholic liver disease, fat builds up in the liver's cells due to increased creation of triglycerides and fatty acids and a decreased ability to break ...
The level of ethanol consumption that minimizes the risk of disease, injury, and death is subject to some controversy. [16] Several studies have found a J-shaped relationship between alcohol consumption and health, [17] [18] [2] [19] meaning that risk is minimized at a certain (non-zero) consumption level, and drinking below or above this level increases risk, with the risk level of drinking a ...
Alcohol use is a major cause of preventable liver disease worldwide, and alcoholic liver disease is the main alcohol-related chronic medical illness. [6] Millions of people of all ages, from adolescents to the elderly, engage in unhealthy drinking. [7] In the United States, excessive alcohol use costs more than $249 billion annually. [8]
Alcohol (also known as ethanol) has a number of effects on health. Short-term effects of alcohol consumption include intoxication and dehydration. Long-term effects of alcohol include changes in the metabolism of the liver and brain, with increased risk of several types of cancer and alcohol use disorder. [1]
Chronic alcohol use is known to lead to liver pathologies, that being alcoholic liver disease, which leads to further liver conditions like FLD or steatosis, which is a buildup of fat in the liver, and cirrhosis, a buildup of scar tissue in the liver tissue. [30]