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Spironolactone has been found to increase LDL ("bad") cholesterol and decrease HDL ("good") cholesterol levels at the relatively high doses used in women with polycystic ovary syndrome (PCOS). [ 149 ] [ 150 ] As such, it may have unfavorable effects on the blood lipid profile in this context.
Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom, and not the underlying cause of the disorder.
Tincture of iodine: iodine in ethanol, or iodine and sodium iodide in a mixture of ethanol and water. Lugol's iodine: iodine and iodide in water alone, forming mostly triiodide. Unlike tincture of iodine, Lugol's iodine has a minimised amount of the free iodine (I 2) component. Iodine glycerin, a preparation used in dentistry.
Spruce Bio, a San Francisco biotech firm, is running a small clinical trial with a drug called tildacerfont for PCOS. It is not clear yet if the oral drug works. President and CFO Samir Gharib ...
Polycystic ovarian syndrome (PCOS): ... Halogen compounds (iodine, bromine, fluorine, and chlorine) ... (an anti-acne drug that can cause an initial purge)
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Not all women with PCOS have difficulty becoming pregnant. For those who do, anovulation is a common cause. The mechanism of this anovulation is uncertain, but there is evidence of arrested antral follicle development, which, in turn, may be caused by abnormal interaction of insulin and luteinizing hormone (LH) on granulosa cells.
It features both a high iodine content, as well as several hydrophilic groups. It is used in clinical diagnostics including arthrography , angiocardiography and urography . [ 2 ] [ 3 ]
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