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  2. List of dopaminergic drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_dopaminergic_drugs

    Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS) and are implicated in many neurological processes, including motivational and incentive salience, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling.

  3. Dopamine reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Dopamine_reuptake_inhibitor

    A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved when extracellular dopamine not absorbed by the postsynaptic neuron is blocked from re-entering the presynaptic neuron.

  4. Motivation-enhancing drug - Wikipedia

    en.wikipedia.org/wiki/Motivation-enhancing_drug

    Some drugs do not appear to increase motivation and can actually have anti-motivational effects. [4] [13] [19] Examples of these drugs include selective serotonin reuptake inhibitors (SSRIs), [19] [20] [21] selective norepinephrine reuptake inhibitors (NRIs), [19] and antipsychotics (which are dopamine receptor antagonists or partial agonists).

  5. Dopamine agonist - Wikipedia

    en.wikipedia.org/wiki/Dopamine_agonist

    The dopamine receptors are members of the G protein-coupled receptors superfamily with seven transmembrane domains. Dopamine receptors have five subtypes, D 1 through D 5, the subtypes can be divided into two subclasses due to their mechanism of action on adenylate cyclase enzyme, D 1-like receptors (D 1 and D 5) and D 2-like receptors (D 2, D ...

  6. Serotonin–norepinephrine–dopamine reuptake inhibitor

    en.wikipedia.org/wiki/Serotonin–norepinephrine...

    Clozapine is an example of a drug used in the treatment of certain CNS disorders, such as schizophrenia, that has superior efficacy precisely because of its broad-spectrum mode of action. Likewise, in cancer chemotherapeutics, it has been recognized that drugs active at more than one target have a higher probability of being efficacious.

  7. Serotonin–dopamine reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Serotonin–dopamine...

    Medifoxamine (Cledial, Gerdaxyl) is an antidepressant that appears to act as an SDRI as well as a 5-HT 2 receptor antagonist. [3] Sibutramine (Reductil, Meridia, Siredia, Sibutrex) is a withdrawn anorectic that itself as a molecule in vitro is an SNDRI but preferentially an SDRI, with 18.3- and 5.8-fold preference for inhibiting the reuptake of serotonin and dopamine over norepinephrine ...

  8. Dopamine antagonist - Wikipedia

    en.wikipedia.org/wiki/Dopamine_antagonist

    A dopamine antagonist, also known as an anti-dopaminergic and a dopamine receptor antagonist (DRA), is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics are dopamine antagonists, and as such they have found use in treating schizophrenia , bipolar disorder , and stimulant psychosis . [ 1 ]

  9. Disorders of diminished motivation - Wikipedia

    en.wikipedia.org/wiki/Disorders_of_diminished...

    DDM can be treated with dopaminergic and other activating medications, such as dopamine reuptake inhibitors, dopamine releasing agents, and dopamine receptor agonists, among others. [ 1 ] [ 2 ] [ 3 ] [ 11 ] These kinds of drugs have also been used by healthy people to improve motivation.