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  2. Catharanthus roseus - Wikipedia

    en.wikipedia.org/wiki/Catharanthus_roseus

    Catharanthus roseus, commonly known as bright eyes, Cape periwinkle, graveyard plant, Madagascar periwinkle, old maid, pink periwinkle, rose periwinkle, [2] is a perennial species of flowering plant in the family Apocynaceae.

  3. Vinca alkaloid - Wikipedia

    en.wikipedia.org/wiki/Vinca_alkaloid

    The Madagascan periwinkle Catharanthus roseus L. is the source for a number of important natural products, [1] including catharanthine and vindoline [2] and the vinca alkaloids it produces from them: leurosine and the chemotherapy agents vinblastine [3] and vincristine, [4] all of which can be obtained from the plant.

  4. Catharanthus - Wikipedia

    en.wikipedia.org/wiki/Catharanthus

    Catharanthus is a genus of flowering plants in the family Apocynaceae.Like the genus Vinca, they are known commonly as periwinkles. [3] There are eight known species. Seven are endemic to Madagascar, [4] though one, C. roseus, is widely naturalized around the world.

  5. Plant sources of anti-cancer agents - Wikipedia

    en.wikipedia.org/wiki/Plant_sources_of_anti...

    Vinca alkaloids were originally manufactured by extracting them from Catharanthus roseus (Madagascar Periwinkle). [1] Podophyllum spp. Two chemotherapy drugs, etoposide and teniposide, are synthetic chemical compounds similar in chemical structure to the toxin podophyllotoxin which is found in Podophyllum peltatum (May Apple). [1] Taxus brevifolia

  6. Flora of Madagascar - Wikipedia

    en.wikipedia.org/wiki/Flora_of_Madagascar

    The diverse flora of Madagascar holds potential for natural product research and drug production on an industrial scale; the Madagascar periwinkle (Cataranthus roseus), a source of alkaloids used in the treatment of different cancers, is a famous example.

  7. Catharanthus trichophyllus - Wikipedia

    en.wikipedia.org/wiki/Catharanthus_trichophyllus

    The plant is a congeneric of the Madagascar periwinkle (C. roseus), the original main source of vinca alkaloids, also known as catharanthus alkaloids, which are still in use today as anticancer drugs. C. trichophyllus contains lower concentrations of such alkaloids. The two species can be hybridized to increase the concentration. [2]

  8. Health care AI, intended to save money, turns out to require ...

    www.aol.com/health-care-ai-intended-save...

    Algorithms are used to predict patients' risk of death or deterioration, to suggest diagnoses or triage patients, to record and summarize visits to save doctors work, and to approve insurance claims.

  9. Dimerization of catharanthine and vindoline - Wikipedia

    en.wikipedia.org/wiki/Dimerization_of...

    Catharanthine and vindoline are terpenoid indole alkaloids naturally produced within the Madagascar periwinkle plant (Catharanthus roseus) whose dimerization produces the anti-cancer drugs vinblastine and vincristine. The precursor of catharanthine and vindoline is strictosidine, the common precursor of all indole alkaloids. [1]

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