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BIRCH (balanced iterative reducing and clustering using hierarchies) is an algorithm used to perform connectivity-based clustering for large data-sets. [7] It is regarded as one of the fastest clustering algorithms, but it is limited because it requires the number of clusters as an input.
In single-linkage clustering, the distance between two clusters is determined by a single pair of elements: those two elements (one in each cluster) that are closest to each other. The shortest of these pairwise distances that remain at any step causes the two clusters whose elements are involved to be merged.
Cluster analysis or clustering is the task of grouping a set of objects in such a way that objects in the same group (called a cluster) are more similar (in some specific sense defined by the analyst) to each other than to those in other groups (clusters).
The standard algorithm for hierarchical agglomerative clustering (HAC) has a time complexity of () and requires () memory, which makes it too slow for even medium data sets. . However, for some special cases, optimal efficient agglomerative methods (of complexity ()) are known: SLINK [2] for single-linkage and CLINK [3] for complete-linkage clusteri
A major step in the module centric analysis is to cluster genes into network modules using a network proximity measure. Roughly speaking, a pair of genes has a high proximity if it is closely interconnected. By convention, the maximal proximity between two genes is 1 and the minimum proximity is 0.
The average silhouette of the data is another useful criterion for assessing the natural number of clusters. The silhouette of a data instance is a measure of how closely it is matched to data within its cluster and how loosely it is matched to data of the neighboring cluster, i.e., the cluster whose average distance from the datum is lowest. [8]
Biclustering, block clustering, [1] [2] Co-clustering or two-mode clustering [3] [4] [5] is a data mining technique which allows simultaneous clustering of the rows and columns of a matrix. The term was first introduced by Boris Mirkin [ 6 ] to name a technique introduced many years earlier, [ 6 ] in 1972, by John A. Hartigan .
In bioinformatics, neighbor joining is a bottom-up (agglomerative) clustering method for the creation of phylogenetic trees, created by Naruya Saitou and Masatoshi Nei in 1987. [1] Usually based on DNA or protein sequence data, the algorithm requires knowledge of the distance between each pair of taxa (e.g., species or sequences) to create the ...