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Some people experience persistent sexual side effects when taking SSRIs or after ... This pushed the patent expiration date from 7 December 2009, to 14 September 2011 ...
What does the expiration date mean? The expiration date is a legal requirement imposed by the FDA since 1979, according to the Harvard Health Letter. The expiration date is supposed to be the date ...
What are SSRIs and what does SSRI stand for? SSRIs are a group of antidepressants known as selective serotonin reuptake inhibitors that work to prevent the brain from reabsorbing serotonin, a key ...
The labeled expiration date is a manufacturer's promise for a time until which the drug will have full efficacy and be safe as manufactured. [4] The labeled expiration date is not an indication of when a drug has become ineffective or unsafe to use. [4] Many drugs are effective for years after their expiration dates. [4]
Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11]
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The SSRIs also have less affinity for α 1, α 2, H 1 and muscarinic receptors, which might explain the differences of adverse events between TCAs and SSRIs. [6] Although SSRIs arrive rapidly to the brain after administration and the effects on 5-HT re-uptake can be measured instantly, it takes about 2–4 weeks to get therapeutic effects. [16]
Antidepressants with a lower half-life, such as paroxetine, duloxetine, and venlafaxine, have been implicated in higher incidences of withdrawal symptoms and more severe withdrawal symptoms. [25] With SSRIs, duration of treatment does not appear associated with the severity of withdrawal symptoms. [24]