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2. Lymph node metastasis - Wikipedia

   en.wikipedia.org/wiki/Lymph_node_metastasis

   Lymphogenic metastasis is a type of regional metastases. This is in contrast to distant metastases, such as bone metastases, liver metastases or brain metastases, which could come from any part of the body. Tumor cells that grow in the lymph nodes can later detach from the lymph node metastases, enter the bloodstream, and lead to distant ...

3. Breast cancer management - Wikipedia

   en.wikipedia.org/wiki/Breast_cancer_management

   N stands for spread to nearby lymph nodes (range of N0-N3) M stands for metastasis (spread to distant parts of the body; either M0 or M1) If the stage is based on removal of the cancer with surgery and review by the pathologist, the letter p (for pathologic) or yp (pathologic after neoadjuvant therapy) may appear before the T and N letters.

4. Metastatic breast cancer - Wikipedia

   en.wikipedia.org/wiki/Metastatic_breast_cancer

   Metastatic breast cancer. Metastatic breast cancer, also referred to as metastases, advanced breast cancer, secondary tumors, secondaries or stage IV breast cancer, is a stage of breast cancer where the breast cancer cells have spread to distant sites beyond the axillary lymph nodes. There is no cure for metastatic breast cancer; [1] there is ...

5. FDA expands approval of breast cancer drug Kisqali to earlier ...

   www.aol.com/news/fda-expands-approval-breast...

   The Food and Drug Administration expanded the approval of Kisqali, a drug for metastatic breast cancer, to also treat patients with earlier stages of the disease, drugmaker Novartis said Tuesday ...

6. Sentinel lymph node - Wikipedia

   en.wikipedia.org/wiki/Sentinel_lymph_node

   The sentinel lymph node is the hypothetical first lymph node or group of nodes draining a cancer. In case of established cancerous dissemination it is postulated that the sentinel lymph nodes are the target organs primarily reached by metastasizing cancer cells from the tumor. The sentinel node procedure (also termed sentinel lymph node biopsy ...

7. TNM staging system - Wikipedia

   en.wikipedia.org/wiki/TNM_staging_system

   N1: regional lymph node metastasis present; at some sites, tumor spread to closest or small number of regional lymph nodes; N2: tumor spread to an extent between N1 and N3 (N2 is not used at all sites) N3: tumor spread to more distant or numerous regional lymph nodes (N3 is not used at all sites) M: presence of distant metastasis. M0: no ...

8. Cervical lymphadenopathy - Wikipedia

   en.wikipedia.org/wiki/Cervical_lymphadenopathy

   Lymph nodes may become enlarged in malignant disease. This cervical lymphadenopathy may be reactive or metastatic. [1] Alternatively, enlarged lymph nodes may represent a primary malignancy of the lymphatic system itself, such as lymphoma (both Hodgkin's and non-Hodgkin's), [6] lymphocytic leukemia, [1] Lymphadenopathy that lasts less than two weeks or more than one year with no progressive ...

9. Metastasis - Wikipedia

   en.wikipedia.org/wiki/Metastasis

   Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; [1] the term is typically used when referring to metastasis by a cancerous tumor. [2] The newly pathological sites, then, are metastases (mets). [3][4] It is generally distinguished from cancer invasion, which is ...