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The two theories; non-adaptive, and adaptive, are used to explain the evolution of senescence, which is the decline in reproduction with age. [8] The non-adaptive theory assumes that the evolutionary deterioration of human age occurs as a result of accumulation of deleterious mutations in the germline. [8]
Aging theories based on group selection; Antagonistic pleiotropy hypothesis; C. Cross-linking theory of aging; D. Disposable Soma Theory; DNA damage theory of aging; E.
Aging theories based on group selection; Antagonistic pleiotropy hypothesis; C. Cross-linking theory of aging; D. Disposable Soma Theory; DNA damage theory of aging; E.
Biogerontology should not be confused with geriatrics, which is a field of medicine that studies the treatment of existing disease in aging people, rather than the treatment of aging itself. There are numerous theories of aging, and no one theory has been entirely accepted.
The metabolic stability theory of aging suggests it is the cells ability to maintain stable concentration of ROS which is the primary determinant of lifespan. [37] This theory criticizes the free radical theory because it ignores that ROS are specific signalling molecules which are necessary for maintaining normal cell functions. [37]
In 1968 it took the form and became known as the neuroendocrine theory of aging. [38] [39] [40] 1956 Denham Harman proposed the free-radical theory of aging and demonstrated that free radical reactions contribute to the degradation of biological systems. [41] The theory is based on the ideas of Rebeca Gerschman and her colleagues put forward in ...
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Ageing (or aging in American English) is the process of becoming older. The term refers mainly to humans , many other animals , and fungi, whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal . [ 1 ]