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Molecular motors are natural (biological) or artificial molecular machines that are the essential agents of movement in living organisms. In general terms, a motor is a device that consumes energy in one form and converts it into motion or mechanical work ; for example, many protein -based molecular motors harness the chemical free energy ...
The prototype of a chemically driven rotary molecular motor by Kelly and co-workers. The motor by Kelly and co-workers is an elegant example of how chemical energy can be used to induce controlled, unidirectional rotational motion, a process which resembles the consumption of ATP in organisms in order to fuel numerous processes. However, it ...
The first example of an artificial molecular machine (a switchable molecular shuttle). The positively charged ring (blue) is initially positioned over the benzidine unit (green), but shifts to the biphenol unit (red) when the benzidine gets protonated (purple) as a result of electrochemical oxidation or lowering of the pH .
Many of these molecular motors are ubiquitous in both prokaryotic and eukaryotic cells, although some, such as those involved with cytoskeletal elements or chromatin, are unique to eukaryotes. The motor protein prestin, [14] expressed in mammalian cochlear outer hair cells, produces mechanical amplification in the cochlea. It is a direct ...
In general terms, a motor is a device that consumes energy in one form and converts it into motion or mechanical work; for example, many protein-based molecular motors harness the chemical free energy released by the hydrolysis of ATP in order to perform mechanical work. [10]
The single-molecule electric motor can be efficiently used in engineering, [2] nanotechnological applications and medicinal applications, [3] where drugs could be delivered to specified locations more accurately. [3] By altering the chemical structure of the molecule, it could become a component of a nanoelectromechanical system (NEMS). It also ...
A proposed branch of research is the integration of molecular motor proteins found in living cells into molecular motors implanted in artificial devices. Such a motor protein would be able to move a "cargo" within that device, via protein dynamics , similarly to how kinesin moves various molecules along tracks of microtubules inside cells.
Eukaryotic cells transport packets of components to particular intracellular locations by attaching them to molecular motors that haul them along microtubules and actin filaments. Since intracellular transport heavily relies on microtubules for movement, the components of the cytoskeleton play a vital role in trafficking vesicles between ...