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Molar pregnancies are relatively rare complications of pregnancy, occurring in approximately 1 in 1,000 pregnancies in the United States, while in Asia, the rates are considerably higher, reaching up to 1 in 100 pregnancies in countries like Indonesia. [4]
In the United States specifically, maternal mortality is still a prevalent issue in health care. From the year 2003 to 2013, only 8 countries worldwide saw an increase of the maternal mortality rate. The United States was included in this group, seeing an increase in the pregnancy-related mortality ratio over the past 3 decades.
Maternal deaths: The annual number of female deaths from any cause related to or aggravated by pregnancy or its management (excluding accidental or incidental causes) during pregnancy and childbirth or within 42 days of termination of pregnancy, irrespective of the duration and site of the pregnancy, expressed per 100,000 live births, for a ...
The term «persistent trophoblastic disease» (PTD) is used when after treatment of a molar pregnancy, some molar tissue is left behind and again starts growing into a tumour. Although PTD can spread within the body like a malignant cancer, the overall cure rate is nearly 100%. [44]
[1] [6] Since 2018, there has been a 4% increase in maternity care deserts in the U.S. [1] In the United States, up to 60,000 women a year experience severe maternal morbidity, life-threatening complications as a result of pregnancy, resulting in up to 700 pregnancy-related deaths annually.
Pregnancy loss is a broad term that is used for miscarriage, ectopic and molar pregnancies. [31] The term foetal death applies variably in different countries and contexts, sometimes incorporating weight, and gestational age from 16 weeks in Norway, 20 weeks in the US and Australia, 24 weeks in the UK to 26 weeks in Italy and Spain.
Gestational choriocarcinoma (GC) is the most aggressive form of trophoblastic tumor; it most commonly arises from certain fertilization defects, such as molar pregnancy, which results in increased level of growth factors and uncontrolled proliferation of trophoblasts in the uterus. [8]
Among other causes of hypercoagulability, Antiphospholipid syndrome has been associated with adverse pregnancy outcomes including recurrent miscarriage. [8] Deep vein thrombosis has an incidence of one in 1,000 to 2,000 pregnancies in the United States, [2] and is the second most common cause of maternal death in developed countries after ...