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  2. Pitolisant - Wikipedia

    en.wikipedia.org/wiki/Pitolisant

    Pitolisant, sold under the brand name Wakix among others, is a medication used for the treatment of excessive daytime sleepiness in adults with narcolepsy. [3] It is an inverse agonist of the histamine H 3 receptor. [3]

  3. Narcolepsy - Wikipedia

    en.wikipedia.org/wiki/Narcolepsy

    Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. [1] The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1]

  4. Stimulant - Wikipedia

    en.wikipedia.org/wiki/Stimulant

    Pitolisant has been shown to be effective and well-tolerated for the treatment of narcolepsy with or without cataplexy. [182] [181] [180] Pitolisant is the only non-controlled anti-narcoleptic drug in the US. [180] It has shown minimal abuse risk in studies. [180] [183]

  5. Sodium oxybate - Wikipedia

    en.wikipedia.org/wiki/Sodium_oxybate

    Sodium oxybate, sold under the brand name Xyrem among others, is a medication used to treat symptoms of narcolepsy: sudden muscle weakness and excessive daytime sleepiness. [3] [8] [9] It is used sometimes in France and Italy as an anesthetic given intravenously.

  6. Axsome's sleep disorder drug succeeds in late-stage trial ...

    www.aol.com/news/axsome-therapeutics-sleep...

    Around 70% of patients with narcolepsy also experience cataplexy episodes, according to U.S. government data, which can cause slurred speech or muscle weakness triggered by intense emotions.

  7. Pediatric narcolepsy - Wikipedia

    en.wikipedia.org/wiki/Pediatric_narcolepsy

    Pediatric narcolepsy cases are cases when patients are diagnosed or experience symptoms onset for narcolepsy before the age of 18. Of patients who obtain a formal diagnosis for narcolepsy, more than 50% report first experiencing symptoms of narcolepsy more than 10 years before their formal diagnosis, with an average age of symptom onset being at age 15 and symptom onset most likely to occur ...

  8. Girl behind the viral video: Oklahoman talks about her ... - AOL

    www.aol.com/news/2015-02-04-girl-behind-the...

    Experts say cataplexy, which is a loss of muscle tone, often accompanies narcolepsy. In the video, Sarah was working on a traditional Japanese dance to send to a choreographer friend ...

  9. Microsleep - Wikipedia

    en.wikipedia.org/wiki/Microsleep

    Modafinil is also being tested across a range of disorders such as schizophrenia, narcolepsy, cataplexy, and sleep apnea. Overall, the trajectory of clinical studies relating to negative symptom microsleeps seems to more thoroughly test modafinil across more disorders and compare new drugs to the efficacy of modafinil to reduce the negative ...

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