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Bipolar disorder is known to have a high heritability. [19] Therefore, sleep disturbances in bipolar disorder could also have a genetic basis. Studies found modest associations between several genes that are known to be associated with the generation and regulation of circadian rhythms and bipolar disorder. [20]
The diagnosis of bipolar disorder can be complicated by coexisting psychiatric conditions including obsessive–compulsive disorder, substance-use disorder, eating disorders, attention deficit hyperactivity disorder, social phobia, premenstrual syndrome (including premenstrual dysphoric disorder), or panic disorder.
The most common sleep-related symptom of bipolar disorder is insomnia, in addition to hypersomnia, nightmares, poor sleep quality, OSA, extreme daytime sleepiness, etc. [27] Moreover, animal models have shown that sleep debt can induce episodes of bipolar mania in laboratory mice, but these models are still limited in their potential to explain ...
Bipolar disorder is a mental disorder with cyclical periods of depression and periods of elevated mood. [1] The elevated mood is significant and is known as mania , a severe elevation that can be accompanied by psychosis in some cases, or hypomania , a milder form of mania.
In addition, certain features have been shown to increase the chances that depressed patients have a bipolar disorder, including atypical symptoms of depression like hypersomnia and hyperphagia, a family history of bipolar disorder, medication-induced hypomania, recurrent or psychotic depression, antidepressant refractory depression, and early ...
Manic episodes can be produced by sleep deprivation in around 30% of people with bipolar. While not all people with bipolar demonstrate seasonality of affective symptoms, it is a consistently reported feature that supports theories of circadian dysfunction in bipolars.
Bipolar I disorder (BD-I; pronounced "type one bipolar disorder") is a type of bipolar spectrum disorder characterized by the occurrence of at least one manic episode, with or without mixed or psychotic features. [1] Most people also, at other times, have one or more depressive episodes. [2]
Co-occurring substance misuse disorders, which are extremely common in bipolar patients, can cause a significant worsening of bipolar symptomatology and can cause the emergence of affective symptoms. The treatment options and recommendations for substance use disorders is wide but may include certain pharmacological and nonpharmacological ...