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Lichen sclerosus (LS) is a chronic, inflammatory skin disease, of unknown cause, which can affect any body part of any person, but has a strong preference for the genitals (penis, vulva), and is also known as balanitis xerotica obliterans when it affects the penis.
In the Usual type VIN, seen more frequently in young patients, lesions tend to be multifocal over an otherwise normal vulvar skin. In the differentiated type VIN, usually seen in postmenopausal women, lesions tend to be isolated and are located over a skin with a vulvar dermatosis such as Lichen slerosus. [4]
Kraurosis vulvae or vulvar lichen sclerosus (VLS) is a cutaneous condition characterized by atrophy and shrinkage of the skin of the vagina and vulva often accompanied by a chronic inflammatory reaction in the deeper tissues.
Vulvar intraepithelial neoplasia (VIN), HPV infection, genital warts, smoking, many sexual partners [1] [3] Diagnostic method: Physical examination, tissue biopsy [1] Differential diagnosis: Lichen sclerosus, hyperplasia [4] Prevention: HPV vaccination [5] Treatment: Surgery, radiation therapy, chemotherapy, biologic therapy [1] Prognosis
Lichen simplex (chronic eczema) Psoriasis; Lichen sclerosus; Lichen planus; Zoon's vulvitis (Zoon's balanitis in men) Pemphigus vulgaris; Pemphigoid (mucous membrane pemphigoid, cicatricial pemphigoid, bullous pemphigoid)
Genital pain and pelvic pain can arise from a variety of conditions, crimes, trauma, medical treatments, physical diseases, mental illness and infections. In some instances the pain is consensual and self-induced. Self-induced pain can be a cause for concern and may require a psychiatric evaluation.
Lupus erythematosus–lichen planus overlap syndrome (lichen planus–lupus erythematosus overlap syndrome) Methotrexate-induced papular eruption; Mixed connective tissue disease (Sharp's syndrome, undifferentiated connective tissue disease) Morphea profunda; Morphea–lichen sclerosus et atrophicus overlap
Morphea–lichen sclerosus et atrophicus overlap is characterized by both lesions of morphea and lichen sclerosus et atrophicus, most commonly seen in women. [ 3 ] : 171 Generalized morphea is characterized by widespread indurated plaques and pigmentary changes, sometimes associated with muscle atrophy, but without visceral involvement.
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