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Recombinant DNA is widely used in biotechnology, medicine and research. Today, recombinant proteins and other products that result from the use of DNA technology are found in essentially every pharmacy, physician or veterinarian office, medical testing laboratory, and biological research laboratory.
The Basics of Recombinant DNA Provides an introduction to the science behind recombinant DNA. The Recombinant DNA Debate Provides more details about the history of the debate surrounding the use of recombinant DNA technology. “Paul Berg: The 1980 Nobel Prize in Chemistry – Autobiography.” Provides an autobiography about Paul Berg.
Molecular cloning takes advantage of the fact that the chemical structure of DNA is fundamentally the same in all living organisms. Therefore, if any segment of DNA from any organism is inserted into a DNA segment containing the molecular sequences required for DNA replication, and the resulting recombinant DNA is introduced into the organism from which the replication sequences were obtained ...
DNA ligases, that join broken DNA together, had been discovered earlier in 1967 [20] and by combining the two enzymes it was possible to "cut and paste" DNA sequences to create recombinant DNA. Plasmids, discovered in 1952, [21] became important tools for transferring information between cells and replicating DNA sequences.
DNA recombination may refer to: Genetic recombination, a natural aspect of DNA repair mechanisms; Homologous recombination, one common form of recombination in eukaryotes; Recombinant DNA technology, in which genetic changes are induced in the laboratory using features of the above mechanisms
DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and ...
1972 – The DNA composition of chimpanzees and gorillas is discovered to be 99% similar to that of humans. 1973 – Stanley Norman Cohen and Herbert Boyer perform the first successful recombinant DNA experiment, using bacterial genes. [6] 1974 – Scientists invent the first biocement for industrial applications.
Recombinant may refer to: Recombinant organism – an organism that contains a different combination of alleles from either of its parents. Recombinant DNA – a form of artificial DNA sequence; Recombinant protein - artificially produced (and often purified) protein; Recombinant virus – a virus formed by recombining genetic material