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Mecasermin, sold under the brand name Increlex, also known as recombinant human insulin-like growth factor-1 (rhIGF-1), is a recombinant form of human insulin-like growth factor 1 (IGF-I) which is used in the long-term treatment of growth failure and short stature in children with severe primary IGF-I deficiency, for instance due to growth hormone deficiency or Laron syndrome (growth hormone ...
Cyclic glycine-proline (cGP) is a metabolite of hormone insulin-like growth factor-1 (IGF-1). It has a cyclic structure, lipophilic nature, and is enzymatically stable which makes it a more favourable candidate for manipulating the binding-release process between IGF-1 and its binding protein, thereby normalising IGF-1 function.
I tested more than 20 different formulas and interviewed a dermatologist and plastic surgeon to create this list of the 9 best growth factor serums of 2023.
Fibroblast growth factor protein was first purified in 1975, but soon afterwards others using different conditions isolated acidic FGF, Heparin-binding growth factor-1, and Endothelial cell growth factor-1. [7] Gene sequencing revealed that this group was actually the same growth factor and that FGF1 was a member of a family of FGF proteins.
The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by a hormone called insulin-like growth factor 1 and by a related hormone called IGF-2. It belongs to the large class of tyrosine kinase receptors. This receptor mediates the effects of IGF-1 ...
Fibroblast growth factor (1 C, 5 P) I. Insulin-like growth factor receptor agonists (8 P) N. Neurotrophic factors (24 P) T. Thrombopoietin receptor agonists (7 P)
Tercica, Inc., was a biopharmaceutical company based in Brisbane, California, United States.It developed Increlex (mecasermin [rDNA origin] injection), also known as recombinant human Insulin-like Growth Factor-1 ().
18736 Ensembl ENSG00000064835 ENSMUSG00000004842 UniProt P28069 Q00286 RefSeq (mRNA) NM_001122757 NM_000306 NM_008849 NM_001362468 RefSeq (protein) NP_000297 NP_001116229 NP_032875 NP_001349397 Location (UCSC) Chr 3: 87.26 – 87.28 Mb Chr 16: 65.32 – 65.33 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse POU class 1 homeobox 1, also known as pituitary-specific positive ...