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A vulnerable plaque is a kind of atheromatous plaque – a collection of white blood cells (primarily macrophages) and lipids (including cholesterol) in the wall of an artery – that is particularly unstable and prone to produce sudden major problems such as a heart attack or stroke. [1]
Stenoses can be slowly progressive, whereas plaque ulceration is a sudden event that occurs specifically in atheromas with thinner/weaker fibrous caps that have become "unstable". [75] Repeated plaque ruptures, ones not resulting in total lumen closure, combined with the clot patch over the rupture and healing response to stabilize the clot is ...
An atheroma, or atheromatous plaque, is an abnormal accumulation of material in the inner layer of an arterial wall. [1] [2]The material consists of mostly macrophage cells, [3] [4] or debris, containing lipids, calcium and a variable amount of fibrous connective tissue.
Atherosclerosis is characterized by the build-up of plaque inside your blood vessels. It can lead to stenosis, which is a narrowing of your artery walls. Plaque is a fatty substance made up of:
The progressive accumulation of plaque within the artery wall over decades leads to the development of unstable vulnerable plaque which can detach as clots leading to strokes and heart attacks. IVUS is of use to determine both plaque volume within the wall of the artery and/or the degree of stenosis of the artery lumen.
She also recommends avoiding retinoids first thing in the a.m., which she calls a well-meaning but misplaced step. “Many retinoids are sun-unstable, and break down in sunlight,” she says ...
The primary factor differentiating unstable angina from stable angina (other than symptoms) is the underlying pathophysiology of the atherosclerosis. The pathophysiology of unstable angina is the reduction of coronary blood flow due to transient platelet aggregation on apparently normal endothelium, coronary artery spasms, or coronary thrombosis.
Rosacea. What it looks like: Rosacea causes redness and thick skin on the face, usually clustered in the center.Easy flushing, a stinging sensation, and small, pus-filled pimples are other common ...