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Clinical trials have confirmed its use in this indication. [57] Malaria: No: No: No: Clinical trials have confirmed its efficacy in both the treatment and prevention of malaria. [58] Pneumocystis jirovecii pneumonia: Yes: Yes: Yes: Its use as a prophylactic treatment is supported by one clinical trial involving children with acute lymphoblastic ...
However, these classifications are based on laboratory behavior. The development of antibiotics has had a profound effect on the health of people for many years. Also, both people and animals have used antibiotics to treat infections and diseases. In practice, both treat bacterial infections. [1]
have had group B streptococcal colonization, bacteriuria, or infection in a previous pregnancy, and have not had a negative test for group B streptococcus by enrichment culture or PCR on a rectovaginal swab sample collected between 35 and 37 weeks' gestation or 3-5 weeks before the anticipated delivery date in the current pregnancy or
Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
Streptococcus bovis is a group of strains of Gram-positive bacteria, originally described as a species, [5] [6] that in humans is associated with urinary tract infections, endocarditis, sepsis, [7] and colorectal cancer. [8]
Bacteriophages have been described for many species of Streptococcus. 18 prophages have been described in S. pneumoniae that range in size from 38 to 41 kb in size, encoding from 42 to 66 genes each. [34] Some of the first Streptococcus phages discovered were Dp-1 [35] [36] and ω1 (alias ω-1).
Post-streptococcal glomerulonephritis (PSGN) is an uncommon complication of either a strep throat or a streptococcal skin infection. It is classified as a type III hypersensitivity reaction. Symptoms of PSGN develop within 10 days following a strep throat or 3 weeks following a GAS skin infection. PSGN involves inflammation of the kidney.
A rapid strep test (also called rapid antigen detection testing or RADT) may also be used. While the rapid strep test is quicker, it has a lower sensitivity (70%) and statistically equal specificity (98%) as a throat culture. [13] In areas of the world where rheumatic fever is uncommon, a negative rapid strep test is sufficient to rule out the ...