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Hemifacial spasm (HFS) is a rare neuromuscular disease characterized by irregular, involuntary muscle contractions on one side (hemi-) of the face (-facial). [1] The facial muscles are controlled by the facial nerve (seventh cranial nerve), which originates at the brainstem and exits the skull below the ear where it separates into five main branches.
Microvascular decompression (MVD), also known as the Jannetta procedure, [1] is a neurosurgical procedure used to treat trigeminal neuralgia (along with other cranial nerve neuralgias), a pain syndrome characterized by severe episodes of intense facial pain, and hemifacial spasm.
[46] [47] Injections are generally administered at intervals of around 10 weeks, with variations based on patient response and usually give fairly quick relief from the muscle spasms. An English study reported that 118 (78%) of 151 patients experienced significant relief of symptoms for a mean duration of 9.2 weeks. [ 11 ]
Oromandibular dystonia (OMD) is a form of focal dystonia that affects varying areas of the head and neck including the lower face, jaw, tongue and larynx. The spasms may cause the mouth to pull open, shut tight, or move repetitively. Speech and swallowing may be distorted.
By 1982, eye muscles had been injected for strabismus and nystagmus (jerky, involuntary eye movements), eyelid muscles for retraction and blepharospasm (sustained, involuntary contractions of muscles around the eye), facial muscles for hemifacial spasm, and limb muscles for dystonia (sustained muscle spasm), all as predicted in Scott's 1973 study.
They would give me treatment, but it was just to keep me stable and prolong my life.” “I remember bawling my eyes out, crying, saying, ‘I'm going to die.’ Grace wasn't even one yet.
In the past, dopamine blocking agents have been used in the treatment of spasmodic torticollis. Treatment was based on the theory that there is an imbalance of the neurotransmitter dopamine in the basal ganglia. These drugs have fallen out of fashion due to various serious side effects: sedation, parkinsonism, and tardive dyskinesia. [16]
Palatal myoclonus is a rare condition in which there are rhythmic jerky movements or a rapid spasm of the palatal (roof of the mouth) muscles. Chronic clonus is often due to lesions of the central tegmental tract (which connects the red nucleus to the ipsilateral inferior olivary nucleus). [citation needed]