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Insulin degludec (INN/USAN) is an ultralong-acting basal insulin analogue that was developed by Novo Nordisk under the brand name Tresiba. [7] It is administered via subcutaneous injection to help control the blood sugar level of those with diabetes .
In general, contraindications to antipsychotic switching are cases in which the risk of switching outweighs the potential benefit. Contraindications to antipsychotic switching include effective treatment of an acute psychotic episode, patients stable on a LAI antipsychotic with a history of poor adherence, and stable patients with a history of self-injurious behavior, violent behavior, or ...
Insulin glargine differs from human insulin by replacing asparagine with glycine in position 21 of the A-chain and by carboxy-terminal extension of B-chain by 2 arginine residues. The arginine amino acids shift the isoelectric point from a pH of 5.4 to 6.7, making the molecule more soluble at an acidic pH and less soluble at physiological pH.
The TCF7L2 allele, for example, increases the risk of developing diabetes by 1.5 times and is the greatest risk of the common genetic variants. [13] Most of the genes linked to diabetes are involved in pancreatic beta cell functions.
The Number Five Crossbar Switching System (5XB switch) is a telephone switch for telephone exchanges designed by Bell Labs and manufactured by Western Electric starting in 1947. It was used in the Bell System principally as a Class 5 telephone switch in the public switched telephone network (PSTN) until the early 1990s, when it was replaced ...
The 5ESS switch has three main types of modules: the Administrative Module (AM) contains the central computers; the Communications Module (CM) is the central time-divided switch of the system; and the Switching Module (SM) makes up the majority of the equipment in most exchanges. The SM performs multiplexing, analog and digital coding, and ...
In building wiring, multiway switching is the interconnection of two or more electrical switches to control an electrical load from more than one location.A common application is in lighting, where it allows the control of lamps from multiple locations, for example in a hallway, stairwell, or large room.
The No. 1 Electronic Switching System Arranged with Data Features (No. 1 ESS ADF) was an adaptation of the Number One Electronic Switching System to create a store and forward message switching system. It used both single and multi-station lines for transmitting teletypewriter and data messages. It was created to respond to a growing need for ...