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Frovatriptan, sold under the brand name Frova, is a triptan drug developed by Vernalis for the treatment of migraine headaches [1] and for short term prevention of menstrual migraine. [2] The product is licensed to Endo Pharmaceuticals in North America and Menarini in Europe.
Sumatriptan [4] binds to 5-HT 1D receptors, zolmitriptan, [5] rizatriptan, [6] naratriptan, [7] almotriptan, [8] and frovatriptan [9] binds to 5-HT 1B/1D and eletriptan [10] binds to 5-HT 1B/1D/1F receptors. Triptans are believed to exert their effects through vasoconstriction, leading to reduced carotid arterial circulation without affecting ...
Triptans have few side effects if used in correct dosage and frequency. The most common adverse effect is recurrence of migraine. A systematic review found that "rizatriptan 10 mg was the only triptan with a recurrence rate greater than that of placebo". [24]
They produce an antimigraine effect by vasoconstriction of the vessels in the brain, as well as inhibiting trigeminal CGRP release and pain transmission. [2] They are normally well tolerated but the vasoconstrictor effects can lead to problematic side effects such as nausea, dizziness and chest discomfort, and therefore require caution in ...
Zolmitriptan, sold under the brand name Zomig among others, is a serotonergic medication which is used in the acute treatment of migraine attacks with or without aura and cluster headaches. [3] It is taken by mouth as a swallowed or disintegrating tablet or as a nasal spray .
A delayed release or late release may refer to: Delayed release (film), the delayed release of a film to the public; Delayed release (pharmacology), oral medicines that do not immediately disintegrate and release the active ingredient(s) into the body [+delayed release], a distinctive feature given to affricate consonants in phonology
The most common side effects [14] reported by at least 2% of patients in controlled trials of sumatriptan (25-, 50-, and 100-mg tablets) for migraine are atypical sensations (paresthesias and warm/cold sensations) reported by 4% in the placebo group and 5–6% in the sumatriptan groups, pain and other pressure sensations (including chest pain ...
Rimegepant, sold under the brand name Nurtec ODT among others, is a medication used for the acute treatment of migraine with or without aura in adults and the prophylactic/ preventive treatment of episodic migraine in adults.
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