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  2. 3,4-Dihydroxyphenylacetaldehyde - Wikipedia

    en.wikipedia.org/wiki/3,4-Dihydroxyphenyl...

    3,4-Dihydroxyphenylacetaldehyde (DOPAL), also known as dopamine aldehyde, is a metabolite of the monoamine neurotransmitter dopamine formed by monoamine oxidase (MAO). [ 2 ] [ 3 ] Other metabolic pathways of dopamine metabolism include methylation by catechol O -methyltransferase (COMT) into 3-methoxytyramine and β-hydroxylation by dopamine β ...

  3. Dopamine - Wikipedia

    en.wikipedia.org/wiki/Dopamine

    A dopamine molecule consists of a catechol structure (a benzene ring with two hydroxyl side groups) with one amine group attached via an ethyl chain. [14] As such, dopamine is the simplest possible catecholamine, a family that also includes the neurotransmitters norepinephrine and epinephrine. [15]

  4. 3-Methoxy-4-hydroxyphenylglycol - Wikipedia

    en.wikipedia.org/wiki/3-Methoxy-4-hydroxyphenyl...

    3-Methoxy-4-hydroxyphenylglycol (MHPG, MOPEG) is a metabolite of norepinephrine degradation.In the brain, it is the principal norepinephrine metabolite. It is released into the blood and cerebrospinal fluid, [1] and a blood sample of it may therefore be an indication of recent sympathetic nervous system activity.

  5. Dopaminergic pathways - Wikipedia

    en.wikipedia.org/wiki/Dopaminergic_pathways

    The dopamine neurons of the dopaminergic pathways synthesize and release the neurotransmitter dopamine. [2] [3] Enzymes tyrosine hydroxylase and dopa decarboxylase are required for dopamine synthesis. [4] These enzymes are both produced in the cell bodies of dopamine neurons. Dopamine is stored in the cytoplasm and vesicles in axon terminals.

  6. L-DOPA - Wikipedia

    en.wikipedia.org/wiki/L-DOPA

    l-DOPA, also known as l-3,4-dihydroxyphenylalanine and used medically as levodopa, is made and used as part of the normal biology of some plants [2] and animals, including humans. Humans, as well as a portion of the other animals that utilize l -DOPA, make it via biosynthesis from the amino acid l -tyrosine .

  7. Elevated plus maze - Wikipedia

    en.wikipedia.org/wiki/Elevated_plus_maze

    The MCSF-test is a behaviour model used to study risk assessment, risk taking, anxiety and security seeking behaviour. It has a completely different design compared to the t-maze, but instead of using a battery of different behaviour models this test can be used to measure a variety of dependent and independent variables.

  8. Dorsolateral prefrontal cortex - Wikipedia

    en.wikipedia.org/wiki/Dorsolateral_prefrontal_cortex

    More specifically, it is theorized that threat-induced anxiety may also be connected to deficits in resolving problems, which leads to uncertainty. [34] When an individual experiences uncertainty, there is increased activity in the DLPFC. In other words, such activity can be traced back to threat-induced anxiety.

  9. Social Phobia Inventory - Wikipedia

    en.wikipedia.org/wiki/Social_Phobia_Inventory

    Social Phobia Inventory (SPIN) is a questionnaire developed by the department of Psychiatry and Behavioral Sciences of Duke University [1] for screening and measuring severity of social anxiety disorder. This self-reported assessment scale consists of 17 items, which cover the main spectrum of social phobia such as fear, avoidance, and ...