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Topical cream formulation is an emulsion semisolid dosage form that is used for skin external application. Most of the topical cream formulations contain more than 20 per cent of water and volatiles and/or less than 50 per cent of hydrocarbons , waxes , or polyethylene glycols as the vehicle for external skin application. [ 1 ]
Acetophenone is formed as a byproduct of the cumene process, the industrial route for the synthesis of phenol and acetone.In the Hock rearrangement of isopropylbenzene hydroperoxide, migration of a methyl group rather than the phenyl group gives acetophenone and methanol as a result of an alternate rearrangement of the intermediate:
British researchers found evidence that using the cream to moisturize areas affected by eczema may actually aggravate the condition. [2] They suggested this was due to skin-thinning effects of a detergent sodium lauryl sulfate. The National Eczema Society recommends alternatives such as white soft paraffin wax or other types of emollient ...
Chemical formula. C 8 H 7 Br O: Molar mass: 199.047 g·mol −1 Appearance ... It is prepared by bromination of acetophenone: [2] C 6 H 5 C(O)CH 3 + Br 2 → C 6 H 5 ...
[3] [1] [6] [10] Gel characteristics include stability, thermodynamic activity, and occlusive properties. [3] [1] [10] Following penetration through the skin barrier, the drug may permeate through deeper skin tissues and reach the blood capillaries in the dermis. [6] [9] It may then proceed to enter the systemic circulation for systemic effect ...
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Products of decomposition of cumene hydroperoxide are methylstyrene, acetophenone, and 2-phenylpropan-2-ol. [3] It is produced by treatment of cumene with oxygen, an autoxidation. At temperatures >100 °C, oxygen is passed through liquid cumene: [4] C 6 H 5 CH(CH 3) 2 + O 2 → C 6 H 5 C(CH 3) 2 OOH. Dicumyl peroxide is a side product.
There are many different types of moisturizers. Petrolatum is one of the most effective moisturizers, although it can be unpopular due to its oily consistency. [9] [10]Other popular moisturizers are cetyl alcohol, cetearyl alcohol, cocoa butter, isopropyl myristate, isopropyl palmitate, lanolin, liquid paraffin, polyethylene glycols, shea butter, silicone oils, stearic acid, stearyl alcohol ...
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