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  2. Losartan - Wikipedia

    en.wikipedia.org/wiki/Losartan

    Besides hypertension, it is also used in diabetic kidney disease, heart failure, and left ventricular enlargement. [4] ... Because losartan can cause hyperkalemia, ...

  3. Angiotensin II receptor blocker - Wikipedia

    en.wikipedia.org/wiki/Angiotensin_II_receptor...

    [citation needed] More recently, they have been used for the treatment of heart failure in patients intolerant of ACE inhibitor therapy, in particular candesartan. Irbesartan and losartan have trial data showing benefit in hypertensive patients with type 2 diabetes, [citation needed] and may delay the progression of diabetic nephropathy.

  4. Drug-induced angioedema - Wikipedia

    en.wikipedia.org/wiki/Drug-induced_angioedema

    The chance of drug-induced angioedema is extremely uncommon, however, as studies show incidence of less than 1%. [4] The reason this adverse effect may occur is due to the build-up of bradykinin, a vasodilator.

  5. Discovery and development of angiotensin receptor blockers

    en.wikipedia.org/wiki/Discovery_and_development...

    Losartan, valsartan, candesartan, irbesartan, telmisartan and olmesartan all contain a biphenyl-methyl group. [citation needed] Losartan is partly metabolized to its 5-carboxylic acid metabolite EXP 3174, which is a more potent AT 1 receptor antagonist than its parent compound [17] and has been a model for the continuing development of several ...

  6. Heart disease is the leading cause of death. Why don't ... - AOL

    www.aol.com/lifestyle/heart-disease-leading...

    Heart diseasecan refer to several types of heart conditions, but the most common in the U.S. is coronary artery disease, which affects blood flow and can lead to a heart attack. The AHA ...

  7. Heart failure - Wikipedia

    en.wikipedia.org/wiki/Heart_failure

    Gynura can cause low blood pressure. Licorice can worsen heart failure by increasing blood pressure and promoting fluid retention. [54] Lily of the Valley can cause abnormally slow heart rates with mechanisms similar to those of digoxin. Tetrandrine can lower blood pressure by inhibiting L-type calcium channels. Yohimbine can exacerbate heart ...

  8. Marijuana use raises risk of heart attack, heart failure and ...

    www.aol.com/marijuana-raises-risk-heart-attack...

    A second study presented Monday followed nearly 160,000 adults with a median age of 54 for about four years to see if use of cannabis would impact their risk of developing heart failure. Heart ...

  9. Simple blood test could predict a person’s heart disease risk ...

    www.aol.com/news/simple-blood-test-could-predict...

    About 13% — roughly 3,600 participants — had either a heart attack or stroke, had surgery to fix a narrowed or blocked artery, or died from heart disease over the 30-year follow-up period.

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