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Bipolar cells receive synaptic input from either rods or cones, or both rods and cones, though they are generally designated rod bipolar or cone bipolar cells. There are roughly 10 distinct forms of cone bipolar cells, however, only one rod bipolar cell, due to the rod receptor arriving later in the evolutionary history than the cone receptor ...
The elements composing the layer of rods and cones (Jacob's membrane) in the retina of the eye are of two kinds, rod cells and cone cells, the former being much more numerous than the latter except in the macula lutea. Jacob's membrane is named after Irish ophthalmologist Arthur Jacob, who was the first to describe this nervous layer of the ...
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Bipolar cells convey impulses from photoreceptors (rods and cones) to ganglion cells, [6] which in turn transport the visual signals to the brain through the optic nerve. Bipolar cells come in two varieties, having either an on-center or an off-center receptive field, each with a surround of the opposite sign.
The photoreceptors (rods and cones) transmit to the bipolar cells, which transmit then to the retinal ganglion cells. Retinal ganglion cell axons collectively form the optic nerve, via which they project to the brain. [8] The rod and cone photoreceptors signal their absorption of photons via a decrease in the release of the neurotransmitter ...
This neurotransmitter hyperpolarizes the bipolar cell. Bipolar cells exist between photoreceptors and ganglion cells and act to transmit signals from the photoreceptors to the ganglion cells. As a result of the bipolar cell being hyperpolarized, it does not release its transmitter at the bipolar-ganglion synapse and the synapse is not excited.
Photograph of the retina of the human eye, with overlay diagrams showing the positions and sizes of the macula, fovea, and optic disc. Perifovea is a region in the retina that circumscribes the parafovea and fovea and is a part of the macula lutea. [1] The perifovea is a belt that covers a 10° radius around the fovea and is 1.5 mm wide.
The blood–ocular barrier is a barrier created by endothelium of capillaries of the retina and iris, ciliary epithelium and retinal pigment epithelium. [1] It is a physical barrier between the local blood vessels and most parts of the eye itself, and stops many substances including drugs from traveling across it. [2]