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Proliferative sickle retinopathy is the most severe ocular complication of sickle cell disease. Even though PSCR begins in the first decade of life, the condition remains asymptomatic and unnoticed until visual symptoms occur due to vitreous hemorrhage or retinal detachment.
Treatment is based on the cause of the retinopathy and may include laser therapy to the retina. Laser photocoagulation therapy has been the standard treatment for many types of retinopathy. Evidence shows that laser therapy is generally safe and improves visual symptoms in sickle cell and diabetic retinopathy.
Hyperviscosity syndrome is a group of symptoms triggered by an increase in the viscosity of the blood. Symptoms of high blood viscosity include spontaneous bleeding from mucous membranes , visual disturbances due to retinopathy , and neurologic symptoms ranging from headache and vertigo to seizures and coma .
[6] [10] This is occurs in the absence of retinal tears or breaks and is most commonly associated with abnormal blood vessel growth due to proliferative diabetic retinopathy. [6] [9] [10] Other causes include trauma, retinal vein occlusion, sickle cell retinopathy, and retinopathy of prematurity. [8] [9] [10] [11]
Diabetes, for example, is the leading cause of new cases of blindness in those aged 20–74, with ocular manifestations such as diabetic retinopathy and macular edema affecting up to 80% of those who have had the disease for 15 years or more.
It could also cause diabetic retinopathy or peripheral neuropathy. Diabetic Retinopathy Symptoms. People with diabetic retinopathy can develop bleeding in the gel-like fluid inside of their eyes.
A new review reports that nine people taking semaglutide and tirzepatide — the active ingredient in GLP-1 medications — experienced vision issues, including three potentially blinding eye ...
It also occurs in diabetes mellitus and is one of the causative factors for microvascular occlusion in diabetic retinopathy. So, the presence of rouleaux can also be a cause of disease because it will restrict the flow of blood throughout the body because capillaries can only accept free-flowing singular and independent red blood cells.