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Lipomas have a prevalence of roughly 2 out of every 100 people. [2] Lipomas typically occur in adults between 40 and 60 years of age. [1] Males are more often affected than females. [1] They are the most common noncancerous soft-tissue tumor. [5] The first use of the term "lipoma" to describe these tumors was in 1709. [6]
Dercum's disease is a rare condition characterized by multiple painful fatty tumors, called lipomas, that can grow anywhere in subcutaneous fat across the body. [1] Sometimes referred as adiposis dolorosa in medical literature, Dercum’s disease is more of a syndrome than a disease (because it has several clinically recognizable features, signs, and symptoms that are characteristic of it and ...
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In 1993, a genetic polymorphism within lipomas was localized to chromosome 12q15, where the HMGIC gene encodes the high-mobility-group protein isoform I-C. [2] This is one of the most commonly found mutations in solitary lipomatous tumors but lipomas often have multiple mutations. Reciprocal translocations involving chromosomes 12q13 and 12q14 ...
[25] Although lipomas can develop at any age, they more commonly appear between the ages of 40 and 60. [24] Lipomas affect about 1% of the population, with no documented sex bias, and about 1 in every 1000 people will have a lipoma within their lifetime. [25] [26] The cause of lipomas is not well defined.
Most are asymptomatic and pain is rare, although some may present with pain before the bumps are noticed. [3] They generally occur bilaterally and display a yellowish to skin-color. [ 3 ] They may feel soft or firm.
When myelolipomas do produce symptoms, it is usually because they have become large, and are pressing on other organs or tissues nearby. Symptoms include pain in the abdomen or flank, blood in the urine, a palpable lump or high blood pressure. [1] As they are benign tumors, myelolipomas do not spread to other body parts.
The change again says there is a possible link between obesity and lipomas due to the mutation, however this is a misinterpretation of the data as I read it. The gene was linked to obesity, it has also now been linked to lipomas. However, just because they have a common start doesn't link obesity and lipoma; a common cause does not prove ...