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Usually 3 - 10 cm (but can be up to 30 cm), oval to round, smooth glistening surface. Usually watery clear to pale yellow cyst fluid but can be viscous and mucoid. Rarely papillary excrescences are seen on outer surface. Cystadenofibroma: Varies from solid areas with knobby papillae to firm confluent areas.
Simple adenosis of the breast is a proliferation of glands with normal 2 cell layer (inner epithelial and outer myoepithelial) configuration involving terminal duct lobular units. It rarely harbors atypia and does not show distortion by fibrosis as seen in other forms of adenosis (e.g. sclerosing, tubular), making diagnosis relatively easy via ...
Definition / general. Refers mainly to fine needle aspiration cytology (FNA) and also includes cytologic examination of imprint, nipple discharge and ductal lavage. Although largely replaced by core needle biopsy, FNA can increase the accuracy rate if both tests are combined, minimizing false negative results of core needle biopsy related to ...
Has a biphasic cellular population: (1) round, fusiform, or polygonal cells with vesicular nuclei and eosinophilic cytoplasm and (2) cells with clear cytoplasm and often eccentrically located nuclei. Solid cystic hidradenoma (Arch Pathol Lab Med 2005;129:e113) Shows both solid and cystic components. Cysts probably represent cystic degeneration.
Ductal carcinoma in situ: DCIS Paget disease. Papillary carcinoma: encapsulated papillary carcinoma solid papillary carcinoma. Breast cancer: histologic grading inflammatory male invasive molecular subtypes multigene products spread and metastases triple negative breast cancer. Therapy: abemaciclib (pending) antibody drug conjugate therapy ...
Melanocytic lesions: atypical melanocytic nevi of the genital type-vulva dysplastic melanocytic nevus melanoma pigmented lesions-vulva. Other tumors: emerging / novel neoplastic entities mixed tumor of vagina. Disorders from other chapters: Merkel cell carcinoma mesonephric adenocarcinoma Vulva & vagina stains: desmin HMGA2 HPV Ki67 p16 p53.
Microscopic (histologic) description. Nonproliferative fibrocystic changes; characterized by 3 features: adenosis, fibrosis and cyst formation. Adenosis: Increased number of acini per lobule. Acini are lined by columnar cells, which may be benign or have atypia. Adenosis is frequently seen in pregnancy and may be focal in nonpregnant women.
Mean size 6 cm (range 1 - 21.5) Usually unilateral (< 10% bilateral) Cystic degeneration in ~25% of cases. Calcifications in ~10% of cases. ~20% present as pedunculated or polypoid growths on ovarian surface. With or without hemorrhage or necrosis. Cellular fibroma: Mean size 8 - 9 cm (range 1 - 19)
Accessed November 8th, 2024. Definition / general. Dermatofibromas (also known as fibrous histiocytomas) are a spectrum of benign dermal based lesions with fibroblastic and histiocytic differentiation. There is debate as to whether dermatofibroma is a reactive or neoplastic process.
Terminology. Eccrine syringofibroadenoma (of Mascaro) Other names include. Eccrine syringofibroadenomatous hyperplasia. Acrosyringeal adenomatosis. Eccrine poromatosis. Linear eccrine poroma. Acrosyringeal nevus or acrosyringeal nevus of Weedon and Lewis. Nevus syringoadenomatosus papilliferum.